SCHEMBL7959841

SCHEMBL7959841

COCCOCOc1c(C#N)ccc(C(Br)C(=O)O)c1OCOCCOC

nearest known ligand 0.35

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
XDH P47989 1/20 0.33
ALDH1A1 P00352 1/20 0.32
HPGD P15428 1/20 0.32
AR P10275 1/20 0.31
F2 P00734 1/20 0.31
ELANE P08246 1/20 0.31
RARG P13631 1/20 0.31
CTNNB1 P35222 1/20 0.30
SSTR2 P30874 1/20 0.30
MMP1 P03956 1/20 0.30
MMP2 P08253 1/20 0.30
MMP3 P08254 1/20 0.30
MMP13 P45452 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8378443 0.85 AR (0.31) AR
SCHEMBL8119442 0.77 XDH (0.35) XDHALDH1A1HPGDARF2
SCHEMBL8377229 0.75 KIF11 (0.32) AR
SCHEMBL7959571 0.73 SSTR2 (0.36) XDHARSSTR2
SCHEMBL22096809 0.70 SSTR2 (0.38) ARSSTR2
SCHEMBL6389982 0.70 SSTR2 (0.39) ARSSTR2
SCHEMBL7962519 0.69 HPGD (0.38) XDHALDH1A1HPGDARF2
SCHEMBL7962058 0.68 RARG (0.34) ALDH1A1F2ELANERARGCTNNB1
SCHEMBL8377243 0.68 TNFRSF1A (0.38) ALDH1A1HPGD
SCHEMBL19781519 0.68 TSHR (0.41) ALDH1A1HPGDARSSTR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6313305-B1 ANTIBIOTICS, BACTERICIDES HOECHST MARION ROUSSEL (FR) 2001-11-06 US disclosed
US-5587372-A BACERICIDES ROUSSEL UCLAF (FR) 1996-12-24 US disclosed
US-5455238-A Bactericides ROUSSEL UCLAF (FR) 1995-10-03 US disclosed