SCHEMBL8377229

SCHEMBL8377229

COCCOCOc1c(C#N)ccc(C(ON)C(=O)OC(c2ccccc2)c2ccccc2)c1OCOCCOC

nearest known ligand 0.32

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
KIF11 P52732 1/20 0.32
AR P10275 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8378443 0.87 AR (0.31) AR
SCHEMBL9065459 0.79 KIF11 (0.33) KIF11
SCHEMBL8133892 0.78 RAB9A (0.33)
SCHEMBL8377231 0.76 IDO1 (0.35) KIF11
SCHEMBL9064970 0.75 LMNA (0.30)
SCHEMBL7961028 0.75 LMNA (0.30)
SCHEMBL7959833 0.75 RARG (0.35) KIF11
SCHEMBL7959841 0.75 XDH (0.33) AR
SCHEMBL9361830 0.75 RARG (0.36) KIF11
SCHEMBL8379337 0.73 KMT2A (0.32) KIF11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5883248-A QUATERNARY AMMONIUM INTERMEDIATES ROUSSEL UCLAF (FR) 1999-03-16 US disclosed
US-5763617-A Cephalosporins ROUSSEL UCLAF (FR) 1998-06-09 US disclosed
US-5712266-A Cephalosporins ROUSSEL UCLAF (FR) 1998-01-27 US disclosed