Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.33 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.33 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.33 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | APP | P05067 | 3/20 | 0.33 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | MAP3K7 | O43318 | 1/20 | 0.33 |
| ▸ | TAB1 | Q15750 | 1/20 | 0.33 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7959273 | 0.91 | L3MBTL1 (0.35) | L3MBTL1KDM4EALDH1A1HPGDHDAC8 | |
| SCHEMBL7952320 | 0.89 | L3MBTL1 (0.42) | L3MBTL1KDM4EALDH1A1HPGDMRGPRX4 | |
| SCHEMBL7953762 | 0.88 | L3MBTL1 (0.38) | L3MBTL1KDM4EALDH1A1HPGDUSP2 | |
| SCHEMBL7945554 | 0.80 | L3MBTL1 (0.34) | L3MBTL1HPGD | |
| SCHEMBL6618750 | 0.79 | L3MBTL1 (0.42) | L3MBTL1KDM4EALDH1A1HPGDLMNA | |
| SCHEMBL7945551 | 0.78 | L3MBTL1 (0.38) | L3MBTL1KDM4EALDH1A1HPGDMRGPRX4 | |
| SCHEMBL8317086 | 0.73 | HDAC8 (0.40) | L3MBTL1KDM4EHDAC8APPMTNR1A | |
| SCHEMBL8321897 | 0.72 | MTNR1A (0.40) | L3MBTL1KDM4EHDAC8APPMTNR1A | |
| SCHEMBL7952302 | 0.72 | L3MBTL1 (0.34) | L3MBTL1 | |
| SCHEMBL13311249 | 0.70 | L3MBTL1 (0.37) | L3MBTL1MRGPRX4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6281354-B1 | ANTIBIOTICS; ANTITUMOR AGENTS | THE SCRIPPS RESEARCH INSTITUTE | 2001-08-28 | — | — | US | disclosed |