Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC1A2 | P43004 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.35 |
| ▸ | HRH1 | P35367 | 1/20 | 0.35 |
| ▸ | DRD3 | P35462 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10886321 | 0.79 | HDAC1 (0.50) | SLC1A2TSHRHDAC1HDAC2CHRM1 | |
| SCHEMBL3103340 | 0.79 | SLC1A2 (0.54) | SLC1A2TSHRHDAC1HDAC2CHRM1 | |
| SCHEMBL4616596 | 0.75 | CA2 (0.50) | SLC1A2HDAC1HDAC2CHRM1AKR1A1 | |
| SCHEMBL4441158 | 0.75 | SLC1A2 (0.47) | SLC1A2TSHRHDAC1HDAC2CHRM1 | |
| Oxalic Acid SCHEMBL27668327 | 0.74 | SLC1A2 (0.50) | SLC1A2TSHRTDP1MEN1KMT2A | |
| SCHEMBL3975057 | 0.74 | HDAC1 (0.39) | TSHRHDAC1HDAC2CHRM1AKR1A1 | |
| SCHEMBL7500371 | 0.74 | GABRR1 (0.46) | SLC1A2HDAC1HDAC2CHRM1AKR1A1 | |
| SCHEMBL9349434 | 0.74 | GPR84 (0.52) | SLC1A2GRIK1GRIK2GPR84FFAR1 | |
| SCHEMBL7055006 | 0.73 | MEN1 (0.46) | SLC1A2TSHRTDP1MEN1KMT2A | |
| SCHEMBL15512497 | 0.72 | GPR84 (0.55) | TSHRTDP1MEN1KMT2AGPR84 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6310076-B1 | TREATING BENIGN PROSTATIC HYPERPLASIA, LOWERING INTRAOCULAR PRESSURE, INHIBITING CHOLESTEROL SYNTHESIS, TREATING DISEASES MEDIATED BY ALPHA-1 RECEPTORS | SYNAPTIC PHARMACEUTICAL CORPORATION | 2001-10-30 | — | — | US | disclosed |