Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | MMP9 | P14780 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | CAD | P27708 | 1/20 | 0.31 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.30 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.30 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.30 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.30 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.30 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.30 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7976055 | 0.95 | KDM4E (0.47) | ALDH1A1TSHRKDM4EUSP2LMNA | |
| SCHEMBL7065794 | 0.90 | ALDH1A1 (0.38) | ALDH1A1TSHRKDM4EUSP2LMNA | |
| SCHEMBL7969892 | 0.88 | ALDH1A1 (0.41) | ALDH1A1TSHRKDM4EUSP2LMNA | |
| SCHEMBL7971325 | 0.85 | KDM4E (0.45) | ALDH1A1TSHRKDM4EUSP2LMNA | |
| SCHEMBL7971358 | 0.85 | TSHR (0.43) | ALDH1A1TSHRKDM4EUSP2LMNA | |
| SCHEMBL7971310 | 0.83 | TSHR (0.44) | ALDH1A1TSHRKDM4EUSP2LMNA | |
| SCHEMBL7971095 | 0.83 | ALDH1A1 (0.42) | ALDH1A1TSHRKDM4EUSP2LMNA | |
| SCHEMBL7973307 | 0.82 | TSHR (0.43) | ALDH1A1TSHRKDM4EUSP2LMNA | |
| SCHEMBL7973197 | 0.81 | KDM4E (0.48) | ALDH1A1TSHRKDM4EUSP2LMNA | |
| SCHEMBL7066614 | 0.79 | ALDH1A1 (0.39) | ALDH1A1TSHRKDM4EUSP2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6172234-B1 | Optically active cyclic amino acid ester derivatives and processes for producing the same | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2001-01-09 | — | — | US | disclosed |
| EP-0976729-A1 | Optically active cyclic amino acid ester derivatives and processes for producing the same | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2000-02-02 | — | — | EP | disclosed |