SCHEMBL7976055

SCHEMBL7976055

CCOC(=O)C(CCCCOS(C)(=O)=O)OS(C)(=O)=O

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.47
USP2 O75604 1/20 0.47
ALDH1A1 P00352 1/20 0.47
LMNA P02545 1/20 0.47
MMP9 P14780 1/20 0.47
ALOX15 P16050 1/20 0.47
TSHR P16473 1/20 0.47
CPB2 Q96IY4 1/20 0.33
L3MBTL1 Q9Y468 3/20 0.32
MAPT P10636 2/20 0.32
CRHBP P24387 1/20 0.32
CRHR2 Q13324 1/20 0.32
MAPK1 P28482 1/20 0.32
TDP1 Q9NUW8 2/20 0.31
MEN1 O00255 1/20 0.31
KMT2A Q03164 1/20 0.31
CAD P27708 1/20 0.30
CA1 P00915 1/20 0.30
CA2 P00918 1/20 0.30
CA9 Q16790 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7960066 0.95 ALDH1A1 (0.44) KDM4EUSP2ALDH1A1LMNAMMP9
SCHEMBL7065794 0.89 ALDH1A1 (0.38) KDM4EUSP2ALDH1A1LMNAMMP9
SCHEMBL7971310 0.88 TSHR (0.44) KDM4EUSP2ALDH1A1LMNAMMP9
SCHEMBL7973307 0.87 TSHR (0.43) KDM4EUSP2ALDH1A1LMNAMMP9
SCHEMBL7973197 0.86 KDM4E (0.48) KDM4EUSP2ALDH1A1LMNAMMP9
SCHEMBL7971358 0.84 TSHR (0.43) KDM4EUSP2ALDH1A1LMNAMMP9
SCHEMBL7969892 0.83 ALDH1A1 (0.41) KDM4EUSP2ALDH1A1LMNAMMP9
SCHEMBL7973393 0.83 ALDH1A1 (0.46) KDM4EUSP2ALDH1A1LMNAMMP9
SCHEMBL7971325 0.81 KDM4E (0.45) KDM4EUSP2ALDH1A1LMNAMMP9
SCHEMBL7064327 0.79 NAAA (0.41) KDM4EUSP2ALDH1A1LMNAMMP9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6172234-B1 Optically active cyclic amino acid ester derivatives and processes for producing the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2001-01-09 US disclosed
EP-0976729-A1 Optically active cyclic amino acid ester derivatives and processes for producing the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2000-02-02 EP disclosed