Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MMP9 | P14780 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 9/20 | 0.40 |
| ▸ | CA2 | P00918 | 9/20 | 0.40 |
| ▸ | CA9 | Q16790 | 8/20 | 0.40 |
| ▸ | CA12 | O43570 | 3/20 | 0.40 |
| ▸ | CA7 | P43166 | 3/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.40 |
| ▸ | CA3 | P07451 | 2/20 | 0.40 |
| ▸ | CA4 | P22748 | 2/20 | 0.40 |
| ▸ | CA6 | P23280 | 2/20 | 0.40 |
| ▸ | CA5A | P35218 | 2/20 | 0.40 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.40 |
| ▸ | NAAA | Q02083 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7971358 | 0.97 | TSHR (0.43) | TSHRKDM4EUSP2ALDH1A1LMNA | |
| SCHEMBL7971310 | 0.96 | TSHR (0.44) | TSHRKDM4EUSP2ALDH1A1LMNA | |
| SCHEMBL7064327 | 0.93 | NAAA (0.41) | TSHRKDM4EUSP2ALDH1A1LMNA | |
| SCHEMBL7969892 | 0.91 | ALDH1A1 (0.41) | TSHRKDM4EUSP2ALDH1A1LMNA | |
| SCHEMBL7066614 | 0.87 | ALDH1A1 (0.39) | TSHRKDM4EUSP2ALDH1A1LMNA | |
| SCHEMBL7976055 | 0.87 | KDM4E (0.47) | TSHRKDM4EUSP2ALDH1A1LMNA | |
| SCHEMBL9294187 | 0.82 | NAAA (0.44) | TSHRALDH1A1LMNANAAAEPHX1 | |
| SCHEMBL7960066 | 0.82 | ALDH1A1 (0.44) | TSHRKDM4EUSP2ALDH1A1LMNA | |
| SCHEMBL9294775 | 0.82 | NAAA (0.44) | TSHRALDH1A1LMNANAAAEPHX1 | |
| SCHEMBL9294659 | 0.82 | NAAA (0.44) | TSHRALDH1A1LMNANAAAEPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6172234-B1 | Optically active cyclic amino acid ester derivatives and processes for producing the same | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2001-01-09 | — | — | US | disclosed |
| EP-0976729-A1 | Optically active cyclic amino acid ester derivatives and processes for producing the same | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2000-02-02 | — | — | EP | disclosed |