Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MMP9 | P14780 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 9/20 | 0.37 |
| ▸ | CA2 | P00918 | 9/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.35 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7971310 | 0.95 | TSHR (0.44) | ALDH1A1TSHRKDM4EUSP2LMNA | |
| SCHEMBL7971358 | 0.94 | TSHR (0.43) | ALDH1A1TSHRKDM4EUSP2LMNA | |
| SCHEMBL7066614 | 0.92 | ALDH1A1 (0.39) | ALDH1A1TSHRKDM4EUSP2LMNA | |
| SCHEMBL7973307 | 0.91 | TSHR (0.43) | ALDH1A1TSHRKDM4EUSP2LMNA | |
| SCHEMBL7960066 | 0.88 | ALDH1A1 (0.44) | ALDH1A1TSHRKDM4EUSP2LMNA | |
| SCHEMBL7064327 | 0.87 | NAAA (0.41) | ALDH1A1TSHRKDM4EUSP2LMNA | |
| SCHEMBL7976055 | 0.83 | KDM4E (0.47) | ALDH1A1TSHRKDM4EUSP2LMNA | |
| SCHEMBL7971325 | 0.83 | KDM4E (0.45) | ALDH1A1TSHRKDM4EUSP2LMNA | |
| SCHEMBL7971095 | 0.80 | ALDH1A1 (0.42) | ALDH1A1TSHRKDM4EUSP2LMNA | |
| SCHEMBL19532519 | 0.78 | ALDH1A1 (0.40) | ALDH1A1TSHRKDM4EUSP2ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6172234-B1 | Optically active cyclic amino acid ester derivatives and processes for producing the same | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2001-01-09 | — | — | US | disclosed |
| EP-0976729-A1 | Optically active cyclic amino acid ester derivatives and processes for producing the same | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2000-02-02 | — | — | EP | disclosed |