Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PYGL | P06737 | 4/20 | 0.59 |
| ▸ | CCKAR | P32238 | 1/20 | 0.58 |
| ▸ | CCKBR | P32239 | 1/20 | 0.58 |
| ▸ | CYP51A1 | Q16850 | 1/20 | 0.53 |
| ▸ | PIN1 | Q13526 | 2/20 | 0.52 |
| ▸ | ALB | P02768 | 2/20 | 0.51 |
| ▸ | IL2 | P60568 | 2/20 | 0.51 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7973132 | 0.85 | TACR1 (0.61) | PIN1 | |
| SCHEMBL7960063 | 0.83 | PYGL (0.55) | PYGLCCKARCCKBRCYP51A1PTGER4 | |
| SCHEMBL29430273 | 0.83 | PYGL (0.55) | PYGLCCKARCCKBRCYP51A1PTGER4 | |
| SCHEMBL7969775 | 0.81 | PYGL (0.66) | PYGLCCKARCCKBRCYP51A1ALB | |
| SCHEMBL8121388 | 0.80 | PYGL (0.55) | PYGLCCKARCCKBRALBIL2 | |
| SCHEMBL7978502 | 0.79 | HDAC3 (0.56) | PIN1 | |
| SCHEMBL7971407 | 0.79 | CCKAR (0.79) | PYGLCCKARCCKBRCYP51A1ALB | |
| SCHEMBL7984929 | 0.78 | F2 (0.59) | PYGLCCKARCCKBRALBIL2 | |
| SCHEMBL16576408 | 0.78 | PIN1 (0.56) | PIN1 | |
| SCHEMBL7971284 | 0.78 | GPR132 (0.56) | PIN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6271247-B1 | BINDING TO NEUROPEPTIDE RECEPTORS | ADIR ET COMPAGNIE (FR) | 2001-08-07 | — | — | US | disclosed |
| US-6172108-B1 | NEUROPEPTIDE Y RECEPTOR LIGANDS; TREATING PSYCHOLOGICAL, EATING, SLEEP, AND SEXUAL DISORDERS; HYPOTENSIVE, ANXIOLYTIC, ANTIDEPRESSANT, AND ANTIDIABETIC AGENTS | ADIR ET COMPAGNIE (FR) | 2001-01-09 | — | — | US | disclosed |
| EP-1010691-A2 | Hydrazide derivatives, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 2000-06-21 | — | — | EP | disclosed |