Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.44 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.44 |
| ▸ | FLT3 | P36888 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | APP | P05067 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.38 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL796534 | 0.84 | TNKS2 (0.46) | RAB9AMAPTSMN1; SMN2TDP1LMNA | |
| SCHEMBL13650900 | 0.81 | LMNA (0.55) | RAB9AMAPTSMN1; SMN2TDP1LMNA | |
| SCHEMBL796212 | 0.81 | RAB9A (0.45) | RAB9AMAPTSMN1; SMN2TDP1LMNA | |
| SCHEMBL8402940 | 0.80 | TNKS2 (0.51) | RAB9AMAPTSMN1; SMN2TDP1LMNA | |
| SCHEMBL9266321 | 0.80 | THRB (0.50) | RAB9AMAPTSMN1; SMN2TDP1LMNA | |
| SCHEMBL84416 | 0.80 | RAB9A (0.64) | RAB9AMAPTSMN1; SMN2TDP1LMNA | |
| SCHEMBL9569354 | 0.78 | MAPT (0.56) | RAB9AMAPTSMN1; SMN2TDP1LMNA | |
| SCHEMBL796769 | 0.78 | MAPT (0.70) | RAB9AMAPTSMN1; SMN2TDP1LMNA | |
| SCHEMBL796869 | 0.76 | THRB (0.47) | RAB9AMAPTSMN1; SMN2TDP1LMNA | |
| SCHEMBL5909037 | 0.76 | LMNA (0.53) | RAB9AMAPTSMN1; SMN2TDP1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120070374-A1 | Compounds for Non-Invasive Measurement of Aggregates of Amyloid Peptides | TECHNISCHE UNIVERSITAT MUNCHEN (DE) | 2012-03-22 | — | — | US | disclosed |
| US-5418248-A | Anticonvulsant, auxiolytic | SYNTHELABO (FR) | 1995-05-23 | — | — | US | disclosed |
| EP-0605295-A1 | Derivatives of 2-thienylimidazo 2,1-b benzothiazole-3-acetic acid, their preparation and their therapeutical use | SYNTHELABO (FR) | 1994-07-06 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120070374-A1 | Compounds for Non-Invasive Measurement of Aggregates of Amyloid Peptides | IAPP, APP, HTT | RAB9A 3627/4885MAPT 10/4885SMN1; SMN2 307/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.