Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.64 |
| ▸ | MAPT | P10636 | 4/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.64 |
| ▸ | TP53 | P04637 | 4/20 | 0.64 |
| ▸ | TSHR | P16473 | 2/20 | 0.64 |
| ▸ | LMNA | P02545 | 1/20 | 0.64 |
| ▸ | ATM | Q13315 | 1/20 | 0.64 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.64 |
| ▸ | NPC1 | O15118 | 4/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | PKM | P14618 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | THRB | P10828 | 2/20 | 0.49 |
| ▸ | FLT3 | P36888 | 1/20 | 0.49 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.49 |
| ▸ | MET | P08581 | 1/20 | 0.48 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.47 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5909037 | 0.89 | LMNA (0.53) | RAB9AMAPTSMN1; SMN2TP53TSHR | |
| SCHEMBL9569335 | 0.88 | THRB (0.53) | RAB9AMAPTSMN1; SMN2TP53TSHR | |
| SCHEMBL10806421 | 0.88 | MAPT (0.52) | RAB9AMAPTSMN1; SMN2TP53TSHR | |
| SCHEMBL9569337 | 0.88 | MAPT (0.52) | RAB9AMAPTSMN1; SMN2TP53TSHR | |
| SCHEMBL2564592 | 0.88 | THRB (0.56) | RAB9AMAPTSMN1; SMN2TP53TSHR | |
| SCHEMBL13650900 | 0.88 | LMNA (0.55) | RAB9AMAPTSMN1; SMN2TP53TSHR | |
| SCHEMBL74089 | 0.88 | MAPT (0.52) | RAB9AMAPTSMN1; SMN2TP53TSHR | |
| SCHEMBL11011641 | 0.87 | MAPT (0.53) | RAB9AMAPTSMN1; SMN2TP53TSHR | |
| SCHEMBL11010264 | 0.85 | MAPT (0.53) | RAB9AMAPTSMN1; SMN2TP53TSHR | |
| SCHEMBL9837374 | 0.85 | RAB9A (0.53) | RAB9AMAPTSMN1; SMN2TP53TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0082712-B1 | 2-PHENYLIMIDAZO(2,1-B)BENZOTHIAZOLE COMPOUNDS, SALTS THEREOF, PROCESS FOR PRODUCING THEM, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1987-06-16 | — | — | EP | claimed |
| US-4464384-A | SUPPRESSANTS OF IMMUNE RESPONSE | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1984-08-07 | — | — | US | claimed |
| EP-0082712-A2 | 2-Phenylimidazo(2,1-b)benzothiazole compounds, salts thereof, process for producing them, and pharmaceutical compositions containing them | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1983-06-29 | — | — | EP | claimed |
| EP-4741401-A1 | BENZOTHIAZOIMIDAZOLYL COMPOUND AND USE THEREOF | ER Stress Research Institute, Inc. (JP) | 2026-05-13 | — | — | EP | disclosed |
| WO-2025009553-A1 | BENZOTHIAZOIMIDAZOLYL COMPOUND AND USE THEREOF | 小胞体ストレス研究所株式会社 | 2025-01-09 | — | — | WO | disclosed |
| CN-118184664-A | Synthetic method of naphtho [1',2', 4,5] imidazo [1,2-a ] pyridine fluorescent compound | 阜阳师范大学 | 2024-06-14 | — | — | CN | disclosed |
| CN-116924867-A | Method for synthesizing trifluoromethyl substituted aromatic hydrocarbon compound | 郑州泰基鸿诺医药股份有限公司 | 2023-10-24 | — | — | CN | disclosed |
| US-11559518-B2 | Endoplasmic reticulum stress regulator comprising benzothiazoimidazolyl compound | ER STRESS RESEARCH INSTITUTE, INC. (JP) | 2023-01-24 | — | — | US | disclosed |
| US-20210386715-A1 | ENDOPLASMIC RETICULUM STRESS REGULATOR COMPRISING BENZOTHIAZOIMIDAZOLYL COMPOUND | ER STRESS RESEARCH INSTITUTE, INC. (JP) | 2021-12-16 | — | — | US | disclosed |
| US-20200295270-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2020-09-17 | — | — | US | disclosed |
| WO-2019068679-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2019-04-11 | — | — | WO | disclosed |
| US-4464384-A | SUPPRESSANTS OF IMMUNE RESPONSE | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1984-08-07 | — | — | US | disclosed |
| US-4464384-A | SUPPRESSANTS OF IMMUNE RESPONSE | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1984-08-07 | — | — | US | disclosed |
| US-4464384-A | SUPPRESSANTS OF IMMUNE RESPONSE | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1984-08-07 | — | — | US | disclosed |
| US-4419289-A | YELLOW COLOR FOR POLYESTERS, POLYAMIDES, AND CELLULOSE ESTERS | EASTMAN KODAK COMPANY (US) | 1983-12-06 | — | — | US | disclosed |
| US-4396547-A | INDOLE, THIADIAZOLE AND MONOAZO DYES | EASTMAN KODAK COMPANY (US) | 1983-08-02 | — | — | US | disclosed |
| EP-0082712-A2 | 2-Phenylimidazo(2,1-b)benzothiazole compounds, salts thereof, process for producing them, and pharmaceutical compositions containing them | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1983-06-29 | — | — | EP | disclosed |
| EP-0082712-A2 | 2-Phenylimidazo(2,1-b)benzothiazole compounds, salts thereof, process for producing them, and pharmaceutical compositions containing them | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1983-06-29 | — | — | EP | disclosed |
| EP-0082712-A2 | 2-Phenylimidazo(2,1-b)benzothiazole compounds, salts thereof, process for producing them, and pharmaceutical compositions containing them | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1983-06-29 | — | — | EP | disclosed |
| US-4354970-A | YELLOW TEXTILE DYE | EASTMAN KODAK COMPANY (US) | 1982-10-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11559518-B2 | Endoplasmic reticulum stress regulator comprising benzothiazoimidazolyl compound | HSPA5, DNAJC10, ERP44 | RAB9A 1684/4885MAPT 3116/4885SMN1; SMN2 2693/4885 |
| US-20210386715-A1 | ENDOPLASMIC RETICULUM STRESS REGULATOR COMPRISING BENZOTHIAZOIMIDAZOLYL COMPOUND | DNAJC10, HSPA5, ERP44 | RAB9A 2027/4885MAPT 3271/4885SMN1; SMN2 2750/4885 |
| US-20200295270-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | L1CAM, EFNA1, EPCAM | RAB9A 2567/4885MAPT 1878/4885SMN1; SMN2 2404/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.