Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 19/20 | 0.48 |
| ▸ | HTR2A | P28223 | 18/20 | 0.48 |
| ▸ | DRD3 | P35462 | 18/20 | 0.48 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7960257 | 0.84 | DRD2 (0.44) | DRD2HTR2ADRD3SLC6A4 | |
| SCHEMBL7957652 | 0.69 | DRD2 (0.55) | DRD2DRD3POLBHTT | |
| SCHEMBL8551459 | 0.69 | DRD2 (0.53) | DRD2HTR2ADRD3SLC6A4 | |
| SCHEMBL8551462 | 0.69 | DRD2 (0.53) | DRD2HTR2ADRD3SLC6A4 | |
| SCHEMBL8703395 | 0.69 | DRD2 (0.61) | DRD2HTR2ADRD3SLC6A4 | |
| SCHEMBL28442559 | 0.68 | SIGMAR1 (0.66) | DRD2POLBHTT | |
| SCHEMBL4503187 | 0.68 | HTR2C (0.46) | DRD2SLC6A4 | |
| SCHEMBL17484538 | 0.68 | KDM4E (0.51) | POLB | |
| SCHEMBL29688968 | 0.68 | HTR2C (0.46) | DRD2SLC6A4 | |
| SCHEMBL8920622 | 0.68 | ALDH1A1 (0.39) | DRD2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6187774-B1 | N-PIPERAZINYLALKYLINDAZOLE DERIVATIVES; PSYCHOLOGICAL DISORDERS, SCHIZOPHRENIA; SIDE EFFECT REDUCTION | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 2001-02-13 | — | — | US | disclosed |
| EP-0885883-A1 | FUSED HETEROCYCLIC COMPOUNDS AND PHARMACEUTICAL APPLICATIONS THEREOF | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1998-12-23 | — | — | EP | disclosed |