Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 3/20 | 0.35 |
| ▸ | MAOA | P21397 | 2/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | PSMB8 | P28062 | 3/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8917923 | 0.88 | MAPT (0.39) | ALDH1A1KDM4EMAPTSMN1; SMN2MEN1 | |
| SCHEMBL8916173 | 0.82 | PTPN1 (0.40) | ALDH1A1MAPTSMN1; SMN2MEN1KMT2A | |
| SCHEMBL29688968 | 0.82 | HTR2C (0.46) | ALDH1A1KDM4EMAPTSMN1; SMN2MEN1 | |
| SCHEMBL8917162 | 0.82 | PTPN1 (0.40) | ALDH1A1KDM4EKMT2ADRD2SLC6A4 | |
| SCHEMBL8918420 | 0.82 | PTPN1 (0.40) | KDM4EKMT2ADRD2SLC6A4HRH4 | |
| SCHEMBL4503187 | 0.82 | HTR2C (0.46) | ALDH1A1KDM4EMAPTSMN1; SMN2MEN1 | |
| SCHEMBL8917953 | 0.81 | PSMB8 (0.40) | ALDH1A1DRD2SLC6A4PSMB8CYP17A1 | |
| SCHEMBL8918815 | 0.81 | ALDH1A1 (0.46) | ALDH1A1KDM4EMAPTSMN1; SMN2MEN1 | |
| Hydrochloric Acid SCHEMBL8916365 | 0.81 | HTR2C (0.47) | ALDH1A1KDM4EMAPTSMN1; SMN2MEN1 | |
| SCHEMBL7700928 | 0.78 | DRD2 (0.55) | ALDH1A1SMN1; SMN2DRD2SLC6A4RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5532240-A | ANTIPSYCHOTIC AGENTS AND ANTISEROTONIN AGENTS | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1996-07-02 | — | — | US | claimed |
| US-5691330-A | ANTIPSYCHOTIC AGENT | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1997-11-25 | — | — | US | disclosed |
| US-5532240-A | ANTIPSYCHOTIC AGENTS AND ANTISEROTONIN AGENTS | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1996-07-02 | — | — | US | disclosed |