Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APEX1 | P27695 | 2/20 | 0.36 |
| ▸ | TTR | P02766 | 1/20 | 0.35 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.34 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.32 |
| ▸ | ALPG | P10696 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | ALPL | P05186 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7958414 | 0.79 | PTGER4 (0.47) | APEX1TTRTAS1R3TAS1R1POLB | |
| SCHEMBL9768897 | 0.74 | TAS1R3 (0.35) | APEX1TTRTAS1R3TAS1R1POLB | |
| SCHEMBL7960304 | 0.73 | APEX1 (0.38) | APEX1TTRTAS1R3TAS1R1POLB | |
| SCHEMBL2030407 | 0.71 | NPSR1 (0.39) | APEX1TTRSMN1; SMN2GLANPC1 | |
| SCHEMBL4301123 | 0.69 | — | — | |
| SCHEMBL7959726 | 0.68 | ELANE (0.53) | POLBL3MBTL1SMN1; SMN2NPC1ALDH1A1 | |
| SCHEMBL3906982 | 0.65 | — | — | |
| SCHEMBL3922006 | 0.63 | TLR8 (0.37) | APEX1TAS1R3TAS1R1POLBSMN1; SMN2 | |
| SCHEMBL13680860 | 0.62 | MAPT (0.32) | APEX1TTRSMN1; SMN2MAPT | |
| SCHEMBL6807398 | 0.62 | ALDH1A1 (0.46) | POLBL3MBTL1ALDH1A1HPGDKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6184245-B1 | Cyclic ketone derivatives and their medical applications | TORAY INDUSTRIES INC. (JP) | 2001-02-06 | — | — | US | disclosed |
| EP-0962456-A1 | CYCLIC KETONE DERIVATIVE AND PHARMACEUTICAL USE THEREOF | TORAY INDUSTRIES, INC. (JP) | 1999-12-08 | — | — | EP | disclosed |