SCHEMBL7960367

SCHEMBL7960367

CC(=O)C(C)Cc1cc[c]c(F)c1

nearest known ligand 0.32

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
HPGD P15428 1/20 0.30
TUBB1 Q9H4B7 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2052825 0.81 ALOX15 (0.33) HPGD
SCHEMBL921395 0.79 GABRA1 (0.40) HPGD
SCHEMBL15163696 0.77 PLA2G1B (0.35) HPGD
SCHEMBL27848147 0.76 POLB (0.40)
SCHEMBL27345820 0.75
SCHEMBL14250280 0.73 SLC1A1 (0.53)
SCHEMBL7966422 0.73 ALDH1A1 (0.47)
SCHEMBL1663606 0.73 TRPA1 (0.31)
SCHEMBL9294568 0.72 HPGD (0.36) HPGDTUBB1
SCHEMBL9293068 0.72 ESR1 (0.48) HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6265581-B1 REACTING SPECIFIED EPOXIDE AND AMINE, REACTING PRODUCT WITH ACID TO FORM ACID ADDITION SALT ELI LILLY AND COMPANY 2001-07-24 US disclosed