Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 1/20 | 0.51 |
| ▸ | DUT | P33316 | 1/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7958314 | 0.83 | HTR2C (0.50) | HTR2C | |
| SCHEMBL7962718 | 0.82 | HTR2C (0.49) | HTR2C | |
| SCHEMBL7958751 | 0.82 | HTR2C (0.53) | HTR2CDUTSIGMAR1 | |
| SCHEMBL7948724 | 0.79 | MCL1 (0.55) | — | |
| SCHEMBL7959061 | 0.78 | HTR2C (0.54) | HTR2CSIGMAR1 | |
| SCHEMBL2038502 | 0.77 | HTR2C (0.63) | HTR2C | |
| SCHEMBL7958387 | 0.76 | HTR2C (0.51) | HTR2C | |
| SCHEMBL7958451 | 0.74 | HTR2C (0.49) | HTR2C | |
| SCHEMBL3245076 | 0.73 | HTR2C (0.66) | HTR2C | |
| SCHEMBL28760998 | 0.72 | HTR2C (0.57) | HTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6323235-B1 | CARDIOVASCULAR DISORDERS, ANTIISCHEMIC AGENTS AND ENZYME INHIBITORS | OHTAKE ATSUSHI (JP) | 2001-11-27 | — | — | US | disclosed |
| EP-0751126-A1 | BENZENE-FUSED HETEROCYCLIC DERIVATIVE AND USE OF THE SAME | TORAY INDUSTRIES, INC. (JP) | 1997-01-02 | — | — | EP | disclosed |