Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.61 |
| ▸ | HCAR3 | P49019 | 5/20 | 0.58 |
| ▸ | PRSS1 | P07477 | 4/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | SLC2A1 | P11166 | 2/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 4/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 3/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | CRHBP | P24387 | 1/20 | 0.50 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.50 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.50 |
| ▸ | RAD52 | P43351 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7971817 | 0.93 | ALDH1A1 (0.63) | SMN1; SMN2HCAR3PRSS1ALDH1A1NPSR1 | |
| SCHEMBL7973678 | 0.87 | SMN1; SMN2 (0.62) | SMN1; SMN2HCAR3PRSS1ALDH1A1SLC2A1 | |
| SCHEMBL7972061 | 0.83 | MAPT (0.75) | SMN1; SMN2HCAR3PRSS1ALDH1A1SLC2A1 | |
| SCHEMBL2552519 | 0.81 | HCAR3 (0.79) | SMN1; SMN2HCAR3PRSS1ALDH1A1MAPT | |
| SCHEMBL10502410 | 0.80 | HCAR3 (0.74) | HCAR3ALDH1A1NPSR1MAPTKMT2A | |
| SCHEMBL7970325 | 0.80 | PTGER4 (0.50) | SMN1; SMN2PRSS1ALDH1A1MAPTPTGER4 | |
| SCHEMBL17208819 | 0.80 | SMN1; SMN2 (0.69) | SMN1; SMN2HCAR3ALDH1A1NPSR1MAPT | |
| SCHEMBL7970570 | 0.80 | KAT2B (0.71) | SMN1; SMN2HCAR3PRSS1ALDH1A1NPSR1 | |
| SCHEMBL6926627 | 0.79 | KMT2A (0.55) | SMN1; SMN2ALDH1A1SLC2A1NPSR1MAPT | |
| SCHEMBL9725429 | 0.79 | PKM (0.65) | SMN1; SMN2HCAR3PRSS1ALDH1A1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6204264-B1 | Benzimidazole derivative, hair growth promoter and external composition for skin using the same | SHISEIDO CO., LTD. (JP) | 2001-03-20 | — | — | US | disclosed |
| EP-0989123-A1 | Benzimidazole derivative, hair growth promoter and external composition for skin using the same | SHISEIDO COMPANY LIMITED (JP) | 2000-03-29 | — | — | EP | disclosed |