Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.63 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.63 |
| ▸ | HCAR3 | P49019 | 6/20 | 0.56 |
| ▸ | MAPT | P10636 | 6/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 3/20 | 0.52 |
| ▸ | NPC1 | O15118 | 2/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.52 |
| ▸ | CRHBP | P24387 | 1/20 | 0.52 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.52 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.52 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | RECQL | P46063 | 1/20 | 0.51 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7960520 | 0.93 | SMN1; SMN2 (0.61) | ALDH1A1NPSR1HCAR3MAPTSMN1; SMN2 | |
| SCHEMBL10502410 | 0.87 | HCAR3 (0.74) | ALDH1A1NPSR1HCAR3MAPTKMT2A | |
| SCHEMBL9725429 | 0.86 | PKM (0.65) | ALDH1A1NPSR1HCAR3MAPTSMN1; SMN2 | |
| SCHEMBL7974178 | 0.86 | ALDH1A1 (0.64) | ALDH1A1NPSR1HCAR3MAPTSMN1; SMN2 | |
| SCHEMBL9725412 | 0.85 | ALDH1A1 (0.63) | ALDH1A1NPSR1HCAR3MAPTSMN1; SMN2 | |
| SCHEMBL2552519 | 0.84 | HCAR3 (0.79) | ALDH1A1HCAR3MAPTSMN1; SMN2KMT2A | |
| SCHEMBL1726083 | 0.83 | MAPT (0.62) | ALDH1A1NPSR1HCAR3MAPTSMN1; SMN2 | |
| SCHEMBL5591699 | 0.83 | ALDH1A1 (0.60) | ALDH1A1NPSR1HCAR3MAPTSMN1; SMN2 | |
| SCHEMBL2335070 | 0.83 | HCAR3 (0.63) | ALDH1A1NPSR1HCAR3MAPTSMN1; SMN2 | |
| SCHEMBL28201836 | 0.83 | ALDH1A1 (0.60) | ALDH1A1NPSR1HCAR3MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6204264-B1 | Benzimidazole derivative, hair growth promoter and external composition for skin using the same | SHISEIDO CO., LTD. (JP) | 2001-03-20 | — | — | US | disclosed |
| CN-1263887-A | Benzimidazole derivative and hair maintaining agent, skin external use agent | SHISEIDO CO LTD (JP) | 2000-08-23 | — | — | CN | disclosed |
| EP-0989123-A1 | Benzimidazole derivative, hair growth promoter and external composition for skin using the same | SHISEIDO COMPANY LIMITED (JP) | 2000-03-29 | — | — | EP | disclosed |