Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR1 | Q92633 | 7/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.38 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.37 |
| ▸ | TTR | P02766 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | HTR2B | P41595 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7959929 | 0.91 | LPAR1 (0.43) | LPAR1KDM4EALDH1A1SMN1; SMN2NPBWR1 | |
| SCHEMBL7960040 | 0.83 | LPAR1 (0.48) | LPAR1KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL8701833 | 0.82 | LPAR1 (0.46) | LPAR1KDM4EALDH1A1SMN1; SMN2NPBWR1 | |
| SCHEMBL7961953 | 0.82 | GPR88 (0.37) | CYP1A2TSHR | |
| SCHEMBL7964513 | 0.82 | LPAR1 (0.43) | LPAR1KDM4EALDH1A1L3MBTL1NPC1 | |
| SCHEMBL7960940 | 0.78 | LPAR1 (0.48) | LPAR1KMT2ANPC1RAB9AGPR139 | |
| SCHEMBL7957895 | 0.78 | LPAR1 (0.46) | LPAR1KDM4ESMN1; SMN2MEN1KMT2A | |
| SCHEMBL7957914 | 0.77 | TAS1R3 (0.44) | LPAR1KDM4ESMN1; SMN2MEN1KMT2A | |
| SCHEMBL27461093 | 0.75 | L3MBTL1 (0.42) | ALDH1A1SMN1; SMN2L3MBTL1CYP2C9TTR | |
| SCHEMBL7960761 | 0.75 | GPR88 (0.49) | L3MBTL1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6172255-B1 | INSECTICIDES; MITICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 2001-01-09 | — | — | US | disclosed |
| US-5830826-A | Alkoxy-alkyl-substituted 1H-3-aryl-pyrrolidine-2, 4-diones used as herbicicides and pesticides | BAYER AKTIENGESELLSCHAFT (DE) | 1998-11-03 | — | — | US | disclosed |