Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR1 | Q92633 | 7/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | GPR88 | Q9GZN0 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7957914 | 0.91 | TAS1R3 (0.44) | LPAR1KDM4ENPC1RAB9APOLB | |
| SCHEMBL7960040 | 0.83 | LPAR1 (0.48) | LPAR1KDM4ENPC1RAB9ACYP2C9 | |
| SCHEMBL8701833 | 0.82 | LPAR1 (0.46) | LPAR1KDM4ENPC1RAB9AALDH1A1 | |
| SCHEMBL7950132 | 0.82 | GPR88 (0.39) | GPR88 | |
| SCHEMBL7958367 | 0.82 | LPAR1 (0.43) | LPAR1KDM4ENPC1RAB9ACYP2C9 | |
| SCHEMBL7960940 | 0.78 | LPAR1 (0.48) | LPAR1NPC1RAB9A | |
| SCHEMBL27387187 | 0.78 | TAS1R3 (0.43) | LPAR1KDM4ECYP2C9POLBTDP1 | |
| SCHEMBL7957895 | 0.78 | LPAR1 (0.46) | LPAR1KDM4ENPC1RAB9A | |
| SCHEMBL7959929 | 0.77 | LPAR1 (0.43) | LPAR1KDM4ENPC1RAB9ATDP1 | |
| SCHEMBL6474679 | 0.75 | L3MBTL1 (0.42) | LPAR1KDM4EPOLBALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6172255-B1 | INSECTICIDES; MITICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 2001-01-09 | — | — | US | disclosed |
| US-5830826-A | Alkoxy-alkyl-substituted 1H-3-aryl-pyrrolidine-2, 4-diones used as herbicicides and pesticides | BAYER AKTIENGESELLSCHAFT (DE) | 1998-11-03 | — | — | US | disclosed |