Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NMT1 | P30419 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 9/20 | 0.49 |
| ▸ | RAB9A | P51151 | 8/20 | 0.49 |
| ▸ | NPC1 | O15118 | 6/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.49 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.48 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 6/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.48 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.47 |
| ▸ | MAPT | P10636 | 5/20 | 0.47 |
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 4/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7947523 | 0.83 | MAPT (0.54) | NMT1SMN1; SMN2RAB9ANPC1GAA | |
| SCHEMBL7959021 | 0.80 | MAPT (0.50) | NMT1SMN1; SMN2RAB9ANPC1GAA | |
| SCHEMBL7961528 | 0.78 | SMN1; SMN2 (0.46) | SMN1; SMN2RAB9ANPC1GAAGPR55 | |
| Dimethylamine SCHEMBL7957188 | 0.76 | GPR55 (0.55) | SMN1; SMN2RAB9ANPC1GAAGPR55 | |
| SCHEMBL7955047 | 0.75 | GPR55 (0.45) | NMT1SMN1; SMN2RAB9ANPC1GAA | |
| SCHEMBL7961699 | 0.75 | SMN1; SMN2 (0.81) | SMN1; SMN2RAB9ANPC1GAAGPR55 | |
| SCHEMBL27522110 | 0.74 | HRH1 (0.71) | RAB9AGAATP53MEN1KMT2A | |
| SCHEMBL3739633 | 0.73 | NPC1 (0.52) | SMN1; SMN2RAB9ANPC1S1PR1S1PR3 | |
| Dimethylamine SCHEMBL7961743 | 0.72 | SMN1; SMN2 (0.67) | SMN1; SMN2RAB9ANPC1GAAGPR55 | |
| SCHEMBL3741053 | 0.72 | NPC1 (0.53) | SMN1; SMN2RAB9ANPC1S1PR1S1PR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6277872-B1 | ANTIISCHEMIC AGENTS; BRAIN DISORDERS | BOEHRINGER INGELHEIM KG (DE) | 2001-08-21 | — | — | US | disclosed |