Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 9/20 | 0.44 |
| ▸ | MAPT | P10636 | 6/20 | 0.44 |
| ▸ | TP53 | P04637 | 5/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 4/20 | 0.44 |
| ▸ | NFKB2 | Q00653 | 4/20 | 0.44 |
| ▸ | RELA | Q04206 | 4/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 7/20 | 0.43 |
| ▸ | NPC1 | O15118 | 6/20 | 0.43 |
| ▸ | NMT1 | P30419 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7959021 | 0.81 | MAPT (0.50) | GPR55SMN1; SMN2MAPTTP53L3MBTL1 | |
| SCHEMBL7947523 | 0.80 | MAPT (0.54) | GPR55SMN1; SMN2MAPTTP53L3MBTL1 | |
| Dimethylamine SCHEMBL7961529 | 0.75 | NMT1 (0.51) | GPR55SMN1; SMN2MAPTTP53L3MBTL1 | |
| SCHEMBL7961699 | 0.69 | SMN1; SMN2 (0.81) | GPR55SMN1; SMN2MAPTTP53L3MBTL1 | |
| SCHEMBL7961528 | 0.68 | SMN1; SMN2 (0.46) | GPR55SMN1; SMN2MAPTTP53L3MBTL1 | |
| SCHEMBL7947708 | 0.67 | CHRNB4 (0.54) | TTRNPSR1 | |
| SCHEMBL7957021 | 0.66 | KDM4E (0.58) | GPR55SMN1; SMN2TP53L3MBTL1ALDH1A1 | |
| SCHEMBL6428833 | 0.66 | SMN1; SMN2 (0.62) | GPR55SMN1; SMN2MAPTTP53L3MBTL1 | |
| SCHEMBL17474439 | 0.65 | KCNH2 (0.53) | MAPTALDH1A1RAB9ANPC1HTT | |
| SCHEMBL7962009 | 0.65 | KDM4E (0.60) | GPR55SMN1; SMN2TP53L3MBTL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6277872-B1 | ANTIISCHEMIC AGENTS; BRAIN DISORDERS | BOEHRINGER INGELHEIM KG (DE) | 2001-08-21 | — | — | US | disclosed |