Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 10/20 | 0.46 |
| ▸ | RAB9A | P51151 | 8/20 | 0.46 |
| ▸ | NPC1 | O15118 | 8/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 6/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.46 |
| ▸ | NOS3 | P29474 | 1/20 | 0.45 |
| ▸ | NOS1 | P29475 | 1/20 | 0.45 |
| ▸ | NOS2 | P35228 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.45 |
| ▸ | MAPT | P10636 | 5/20 | 0.45 |
| ▸ | MEN1 | O00255 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 4/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Dimethylamine SCHEMBL7961529 | 0.78 | NMT1 (0.51) | SMN1; SMN2RAB9ANPC1GAAGPR55 | |
| SCHEMBL6428833 | 0.74 | SMN1; SMN2 (0.62) | SMN1; SMN2RAB9ANPC1GAAGPR55 | |
| SCHEMBL7947523 | 0.74 | MAPT (0.54) | SMN1; SMN2RAB9ANPC1GAAGPR55 | |
| SCHEMBL7959021 | 0.73 | MAPT (0.50) | SMN1; SMN2RAB9ANPC1GAAGPR55 | |
| SCHEMBL7961699 | 0.72 | SMN1; SMN2 (0.81) | SMN1; SMN2RAB9ANPC1GAAGPR55 | |
| SCHEMBL7956985 | 0.69 | KMT2A (0.55) | SMN1; SMN2RAB9ANPC1GAAGPR55 | |
| Irampanel SCHEMBL678128 | 0.69 | HTR7 (0.63) | SMN1; SMN2RAB9ANPC1GAAGPR55 | |
| Irampanel SCHEMBL6879876 | 0.68 | HTR7 (0.62) | SMN1; SMN2RAB9ANPC1GAAGPR55 | |
| SCHEMBL7955047 | 0.68 | GPR55 (0.45) | SMN1; SMN2RAB9ANPC1GAAGPR55 | |
| SCHEMBL7957183 | 0.68 | SMN1; SMN2 (0.50) | SMN1; SMN2RAB9ANPC1GAAGPR55 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6277872-B1 | ANTIISCHEMIC AGENTS; BRAIN DISORDERS | BOEHRINGER INGELHEIM KG (DE) | 2001-08-21 | — | — | US | disclosed |