Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGDS | O60760 | 2/20 | 0.56 |
| ▸ | TSHR | P16473 | 2/20 | 0.54 |
| ▸ | CFTR | P13569 | 1/20 | 0.54 |
| ▸ | P4HTM | Q9NXG6 | 2/20 | 0.51 |
| ▸ | OXTR | P30559 | 1/20 | 0.49 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.49 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.49 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.49 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.49 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | CRHBP | P24387 | 1/20 | 0.46 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8425714 | 0.96 | HPGDS (0.60) | HPGDSTSHRCFTRP4HTMOXTR | |
| SCHEMBL7952466 | 0.90 | HPGDS (0.52) | HPGDSTSHRCFTRP4HTMOXTR | |
| SCHEMBL8429920 | 0.85 | HPGDS (0.49) | HPGDSTSHRCFTRP4HTMOXTR | |
| SCHEMBL1003508 | 0.75 | HDAC1 (0.71) | TSHRCFTRHDAC3HDAC1HDAC7 | |
| SCHEMBL8359492 | 0.75 | KMT2A (0.76) | TSHRCFTRHDAC3HDAC1HDAC7 | |
| SCHEMBL29913684 | 0.74 | P4HTM (0.74) | HPGDSP4HTML3MBTL1GAATP53 | |
| SCHEMBL687378 | 0.74 | P4HTM (0.74) | HPGDSP4HTML3MBTL1GAATP53 | |
| SCHEMBL29488117 | 0.73 | P4HTM (0.71) | HPGDSP4HTML3MBTL1GAATP53 | |
| Hydrochloric Acid SCHEMBL29488111 | 0.73 | P4HTM (0.71) | HPGDSP4HTML3MBTL1GAATP53 | |
| SCHEMBL6843722 | 0.72 | ALDH1A1 (0.68) | TSHRCFTRHDAC3HDAC1HDAC7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6187928-B1 | TREATING FUNGAL DISEASES | THE ROCKEFELLER UNIVERSITY | 2001-02-13 | — | — | US | disclosed |
| US-6087510-A | Method of use of imidazolium cations | THE ROCKEFELLER UNIVERSITY (US) | 2000-07-11 | — | — | US | disclosed |
| US-5969150-A | FLUORESCENT COMPOUNDS FOR MEDICAL DIAGNOSIS, DRUGS AND LABELS OR FUNGICIDES AND VIRICIDES | THE ROCKEFELLER UNIVERSITY (US) | 1999-10-19 | — | — | US | disclosed |