Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGDS | O60760 | 2/20 | 0.49 |
| ▸ | OXTR | P30559 | 2/20 | 0.48 |
| ▸ | AVPR1A | P37288 | 2/20 | 0.48 |
| ▸ | GPBAR1 | Q8TDU6 | 3/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | CFTR | P13569 | 1/20 | 0.45 |
| ▸ | P4HTM | Q9NXG6 | 2/20 | 0.44 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.43 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8425714 | 0.89 | HPGDS (0.60) | HPGDSOXTRAVPR1ATSHRCFTR | |
| SCHEMBL7961749 | 0.85 | HPGDS (0.56) | HPGDSOXTRAVPR1ATSHRCFTR | |
| SCHEMBL7952466 | 0.83 | HPGDS (0.52) | HPGDSOXTRAVPR1ATSHRCFTR | |
| SCHEMBL6785255 | 0.73 | LMNA (0.51) | GPBAR1LPAR1KMT2AGAA | |
| SCHEMBL6780567 | 0.71 | GPBAR1 (0.49) | GPBAR1TSHRKMT2AGAA | |
| SCHEMBL6235626 | 0.71 | GPBAR1 (0.47) | GPBAR1CFTRHDAC3HDAC1HDAC6 | |
| SCHEMBL8359492 | 0.69 | KMT2A (0.76) | TSHRCFTRLPAR1HDAC3HDAC1 | |
| SCHEMBL1003508 | 0.69 | HDAC1 (0.71) | TSHRCFTRHDAC3HDAC1HDAC7 | |
| SCHEMBL22100277 | 0.69 | OXTR (0.48) | HPGDSOXTRAVPR1AHDAC3HDAC1 | |
| SCHEMBL5353976 | 0.68 | MEN1 (0.71) | TSHRCFTRLPAR1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5874587-A | FLUORESCENCE | THE ROCKEFELLER UNIVERSITY (US) | 1999-02-23 | — | — | US | disclosed |