Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | GALR2 | O43603 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | PGK1 | P00558 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | CCR6 | P51684 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | CTSB | P07858 | 1/20 | 0.36 |
| ▸ | CTSH | P09668 | 1/20 | 0.36 |
| ▸ | MPI | P34949 | 2/20 | 0.35 |
| ▸ | PMM2 | O15305 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7594307 | 0.79 | KMT2A (0.38) | LMNAGALR2POLBPGK1CYP1A2 | |
| SCHEMBL31530747 | 0.78 | LMNA (0.57) | LMNAGALR2POLBPGK1CYP1A2 | |
| SCHEMBL8552936 | 0.78 | LMNA (0.57) | LMNAGALR2POLBPGK1CYP1A2 | |
| SCHEMBL31530748 | 0.78 | LMNA (0.57) | LMNAGALR2POLBPGK1CYP1A2 | |
| SCHEMBL7960036 | 0.78 | ALDH1A1 (0.40) | LMNAGALR2POLBCYP1A2ALDH1A1 | |
| SCHEMBL8556955 | 0.77 | GAA (0.51) | LMNAGALR2POLBPGK1CYP1A2 | |
| SCHEMBL7472156 | 0.75 | GRIN2D (0.43) | LMNAPOLBPGK1ALDH1A1SMN1; SMN2 | |
| SCHEMBL7472075 | 0.75 | MEN1 (0.48) | POLBCYP1A2ALDH1A1SMN1; SMN2TDP1 | |
| SCHEMBL23749957 | 0.73 | TDP1 (0.40) | POLBPGK1CYP1A2ALDH1A1SMN1; SMN2 | |
| SCHEMBL8078944 | 0.73 | ALDH1A1 (0.45) | LMNAPOLBALDH1A1SMN1; SMN2TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6172065-B1 | CENTRAL NERVOUS SYSTEM DISORDERS | WARNER-LAMBERT COMPANY | 2001-01-09 | — | — | US | disclosed |
| WO-1998023599-A1 | UREA AND THIOUREA DERIVATIVES OF SUBSTITUTED QUINOXALINE 2,3-DIONES AS GLUTAMATE RECEPTOR ANTAGONISTS | WARNER-LAMBERT COMPANY (US) | 1998-06-04 | — | — | WO | disclosed |