SCHEMBL8556955

SCHEMBL8556955

Cc1cc2nc(Cl)c(Cl)nc2cc1[N+](=O)[O-]

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 2/20 0.51
POLB P06746 2/20 0.49
LMNA P02545 2/20 0.49
GALR2 O43603 1/20 0.49
PGK1 P00558 1/20 0.46
TSHR P16473 4/20 0.42
CYP3A4 P08684 3/20 0.42
ALDH1A1 P00352 2/20 0.42
RECQL P46063 1/20 0.42
MPI P34949 1/20 0.40
GRM6 O15303 1/20 0.40
GRIA1 P42261 1/20 0.40
GRIA2 P42262 1/20 0.40
GRIA3 P42263 1/20 0.40
GRIA4 P48058 1/20 0.40
MAPT P10636 2/20 0.40
CYP2C9 P11712 1/20 0.39
HPGD P15428 1/20 0.39
APEX1 P27695 1/20 0.39
BLM P54132 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31530747 0.86 LMNA (0.57) GAAPOLBLMNAGALR2PGK1
SCHEMBL8552936 0.86 LMNA (0.57) GAAPOLBLMNAGALR2PGK1
SCHEMBL31530748 0.86 LMNA (0.57) GAAPOLBLMNAGALR2PGK1
SCHEMBL19213941 0.83 GAA (0.57) GAAPOLBLMNAGALR2PGK1
SCHEMBL8893038 0.81 POLB (0.47) GAAPOLBLMNAGALR2PGK1
SCHEMBL1291907 0.81 PGK1 (0.61) POLBLMNAGALR2PGK1TSHR
SCHEMBL6605146 0.78 MAPT (0.49) GAAPOLBLMNAPGK1TSHR
SCHEMBL5722727 0.78 POLB (0.44) GAAPOLBLMNAGALR2PGK1
SCHEMBL7961783 0.77 LMNA (0.41) GAAPOLBLMNAGALR2PGK1
SCHEMBL21591902 0.77 GAA (0.48) GAAPOLBLMNAGALR2PGK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0573635-B1 COMPOSITION AND USE OF SUBSTITUTED 1,3-DITHIOLO- AND 1,4-DITHIINOQUINOXALINES AS AN ANTIMICROBIAL DOW CHEMICAL CO (US) 1998-07-08 EP disclosed
EP-0784083-A2 Composition and use of substituted 1,3-dithiolo-and 1,4-dithiinoquinoxalines as an antimicrobial THE DOW CHEMICAL COMPANY (US) 1997-07-16 EP disclosed
EP-0573635-A1 COMPOSITION AND USE OF SUBSTITUTED 1,3-DITHIOLO- AND 1,4-DITHIINOQUINOXALINES AS AN ANTIMICROBIAL THE DOW CHEMICAL COMPANY (US) 1993-12-15 EP disclosed
WO-1993013106-A1 COMPOSITION AND USE OF SUBSTITUTED 1,3-DITHIOLO- AND 1,4-DITHIINOQUINOXALINES AS AN ANTIMICROBIAL THE DOW CHEMICAL COMPANY (US) 1993-07-08 WO disclosed
US-5200409-A For preventing growth of marine organisms on an exposed surface THE DOW CHEMICAL COMPANY (US) 1993-04-06 US disclosed