Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB11 | O95342 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | TTR | P02766 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | BACE1 | P56817 | 2/20 | 0.44 |
| ▸ | F2 | P00734 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.41 |
| ▸ | TNFSF11 | O14788 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL919577 | 0.89 | ALDH1A1 (0.55) | KMT2ALMNAMEN1CYP3A4MAPT | |
| SCHEMBL4797077 | 0.87 | LMNA (0.46) | ABCB11KMT2ALMNAMEN1CYP3A4 | |
| SCHEMBL6194628 | 0.82 | CYP3A4 (0.55) | KMT2ALMNAMEN1CYP3A4MAPT | |
| SCHEMBL14707645 | 0.82 | LMNA (0.55) | KMT2ALMNAMEN1CYP3A4MAPT | |
| SCHEMBL10765006 | 0.80 | KMT2A (0.44) | KMT2ALMNAMEN1CYP3A4MAPT | |
| SCHEMBL4637234 | 0.80 | CYP3A4 (0.53) | ABCB11KMT2ALMNAMEN1CYP3A4 | |
| SCHEMBL16954598 | 0.80 | KMT2A (0.48) | KMT2ALMNAMEN1CYP3A4MAPT | |
| SCHEMBL2010436 | 0.80 | LMNA (0.59) | KMT2ALMNAMEN1CYP3A4MAPT | |
| SCHEMBL14700551 | 0.80 | KMT2A (0.46) | KMT2ALMNAMEN1CYP3A4MAPT | |
| SCHEMBL16960587 | 0.80 | KMT2A (0.44) | KMT2ALMNAMEN1CYP3A4MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1080258-C | 1-H-3-aryl-pyrrolidine-2, 4-dione derivatives as pesticides | BAYER AG (DE) | 2002-03-06 | — | — | CN | disclosed |
| US-6255301-B1 | CARDIOVASCULAR DISORDERS; ANTICOAGULANT; PROTEASE INHIBITORS | ASTRAZENECA AB (SE) | 2001-07-03 | — | — | US | disclosed |