Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | TP53 | P04637 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | TTR | P02766 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | BACE1 | P56817 | 2/20 | 0.44 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | F2 | P00734 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | RXRA | P19793 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16953510 | 0.92 | LMNA (0.50) | KMT2AMEN1SMN1; SMN2TP53KDM4E | |
| SCHEMBL919577 | 0.89 | ALDH1A1 (0.55) | KMT2AMEN1SMN1; SMN2ALDH1A1TP53 | |
| SCHEMBL13725392 | 0.86 | RXRA (0.53) | KMT2AMEN1SMN1; SMN2ALDH1A1TP53 | |
| SCHEMBL40552 | 0.85 | ALDH1A1 (0.61) | KMT2AMEN1SMN1; SMN2ALDH1A1NPC1 | |
| SCHEMBL16533898 | 0.85 | CA1 (0.50) | KMT2AMEN1SMN1; SMN2ALDH1A1TP53 | |
| SCHEMBL16290846 | 0.83 | PDE4A (0.54) | KMT2AMEN1SMN1; SMN2ALDH1A1TP53 | |
| SCHEMBL20836735 | 0.83 | PDE4A (0.54) | KMT2AMEN1SMN1; SMN2ALDH1A1TP53 | |
| SCHEMBL16955368 | 0.82 | KMT2A (0.43) | KMT2AMEN1SMN1; SMN2ALDH1A1TP53 | |
| SCHEMBL6194628 | 0.82 | CYP3A4 (0.55) | KMT2AMEN1SMN1; SMN2ALDH1A1TP53 | |
| SCHEMBL14707645 | 0.82 | LMNA (0.55) | KMT2AMEN1SMN1; SMN2ALDH1A1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2900645-A1 | 3-PHENYLISOXAZOLIN DERIVATIVES WITH HERBICIDAL ACTION | Bayer CropScience AG (DE) | 2015-08-05 | — | — | EP | disclosed |