Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.72 |
| ▸ | KDR | P35968 | 3/20 | 0.50 |
| ▸ | BRAF | P15056 | 2/20 | 0.50 |
| ▸ | HPGDS | O60760 | 1/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | LDHA | P00338 | 1/20 | 0.46 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.46 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.44 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.44 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | HTR2C | P28335 | 1/20 | 0.44 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15507078 | 0.86 | BAZ2B (0.79) | BAZ2BHPGDSRXFP1NPC1LDHA | |
| SCHEMBL1542986 | 0.84 | BAZ2B (1.00) | BAZ2BHPGDSNPC1LDHAATM | |
| SCHEMBL7962334 | 0.83 | BAZ2B (0.74) | BAZ2BHPGDSP4HTMSMN1; SMN2MAPT | |
| SCHEMBL20057794 | 0.82 | BAZ2B (0.68) | BAZ2BHPGDSRXFP1NPC1LDHA | |
| SCHEMBL4412321 | 0.81 | MAPT (0.55) | BAZ2BHPGDSRXFP1NPC1LDHA | |
| SCHEMBL5648046 | 0.80 | LDHA (0.71) | BAZ2BRXFP1NPC1LDHAP4HTM | |
| SCHEMBL1132053 | 0.79 | HDAC2 (0.57) | KDRNPC1SMN1; SMN2DEGS1GAA | |
| SCHEMBL12409679 | 0.79 | BAZ2B (0.65) | BAZ2BRXFP1NPC1ATMSMN1; SMN2 | |
| SCHEMBL11009430 | 0.79 | MAP4K4 (0.60) | HPGDSRXFP1NPC1LDHASMN1; SMN2 | |
| SCHEMBL13876398 | 0.78 | SMN1; SMN2 (0.54) | BAZ2BHPGDSNPC1SMN1; SMN2RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11572374-B2 | N-cyano-7-azanorbornane derivatives and uses thereof | AMGEN INC. (US) | 2023-02-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11572374-B2 | N-cyano-7-azanorbornane derivatives and uses thereof | CYP3A7, CYP51A1, NT5C3B | BAZ2B 3384/4885KDR 3225/4885BRAF 4635/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.