Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.68 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.47 |
| ▸ | HPGDS | O60760 | 1/20 | 0.45 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | LDHA | P00338 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 2/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.43 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.42 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.42 |
| ▸ | GRM5 | P41594 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.41 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.40 |
| ▸ | PRKDC | P78527 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15507078 | 0.83 | BAZ2B (0.79) | BAZ2BGPR119HPGDSRXFP1NPC1 | |
| SCHEMBL24976756 | 0.82 | BAZ2B (0.72) | BAZ2BGPR119HPGDSRXFP1NPC1 | |
| SCHEMBL1542986 | 0.81 | BAZ2B (1.00) | BAZ2BHPGDSNPC1LDHAATM | |
| SCHEMBL2551254 | 0.81 | LDHA (0.67) | BAZ2BHPGDSRXFP1NPC1LDHA | |
| SCHEMBL24212110 | 0.81 | HDAC6 (0.53) | ALDH1A1MKNK1MKNK2SMN1; SMN2 | |
| SCHEMBL7962334 | 0.81 | BAZ2B (0.74) | BAZ2BHPGDSMAPTMKNK1MKNK2 | |
| SCHEMBL944150 | 0.79 | HDAC2 (0.59) | ALDH1A1MKNK1MKNK2SMN1; SMN2 | |
| SCHEMBL12409679 | 0.77 | BAZ2B (0.65) | BAZ2BRXFP1NPC1ATMPTPN1 | |
| SCHEMBL30747787 | 0.75 | CYP11B1 (0.56) | RXFP1NPC1LDHAALDH1A1RAB9A | |
| SCHEMBL28682644 | 0.75 | CYP11B1 (0.56) | RXFP1NPC1LDHAALDH1A1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2892888-B1 | N-CYCLOPROPYL-N-PIPERIDINYL-AMIDES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM, AND USES THEREOF | BOEHRINGER INGELHEIM INT (DE) | 2018-04-18 | — | — | EP | disclosed |