Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.40 |
| ▸ | PPARA | Q07869 | 6/20 | 0.40 |
| ▸ | PPARG | P37231 | 5/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | PPARD | Q03181 | 1/20 | 0.34 |
| ▸ | ELANE | P08246 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | FABP4 | P15090 | 1/20 | 0.32 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7976476 | 0.89 | PPARA (0.42) | LMNAKDM4EPOLBMAPTCYP19A1 | |
| SCHEMBL7972678 | 0.80 | ALDH1A1 (0.45) | KDM4EPPARAPPARGSMN1; SMN2LTB4R | |
| SCHEMBL7976460 | 0.78 | PPARA (0.39) | LMNAMAPTCYP19A1PPARAPPARG | |
| SCHEMBL7974197 | 0.78 | MRGPRX4 (0.51) | PPARAPPARGSMN1; SMN2LTB4RALDH1A1 | |
| SCHEMBL7526340 | 0.77 | DDB1 (0.44) | LMNAKDM4EPOLBMAPTCYP19A1 | |
| SCHEMBL6957074 | 0.76 | MAPT (0.59) | LMNAKDM4EPOLBMAPTCYP19A1 | |
| SCHEMBL7962749 | 0.75 | SMN1; SMN2 (0.48) | CYP19A1PPARAPPARGSMN1; SMN2MEN1 | |
| SCHEMBL7962734 | 0.75 | SMN1; SMN2 (0.48) | CYP19A1PPARAPPARGSMN1; SMN2ACHE | |
| SCHEMBL7974327 | 0.75 | PPARA (0.42) | LMNAMAPTPPARAPPARGSMN1; SMN2 | |
| SCHEMBL7665918 | 0.74 | LMNA (0.49) | LMNAKDM4EPOLBMAPTCYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6248766-B1 | CARDIOVASCULAR DISORDERS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2001-06-19 | — | — | US | disclosed |