Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 7/20 | 0.42 |
| ▸ | PPARG | P37231 | 6/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.37 |
| ▸ | PPARD | Q03181 | 1/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | FABP4 | P15090 | 1/20 | 0.34 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7962763 | 0.89 | LMNA (0.42) | PPARAPPARGACHESMN1; SMN2LTB4R | |
| SCHEMBL7962739 | 0.83 | ACHE (0.37) | ACHECYP19A1LMNAKDM4EPOLB | |
| SCHEMBL7976450 | 0.81 | ACHE (0.36) | PPARAPPARGACHEPPARDCYP19A1 | |
| SCHEMBL7976460 | 0.81 | PPARA (0.39) | PPARAPPARGSMN1; SMN2LTB4RPPARD | |
| SCHEMBL7962737 | 0.81 | ABCB1 (0.39) | PPARAPPARGACHEPPARDCYP19A1 | |
| SCHEMBL7976448 | 0.79 | KDM4E (0.36) | PPARAPPARGACHESMN1; SMN2PPARD | |
| SCHEMBL7972678 | 0.78 | ALDH1A1 (0.45) | PPARAPPARGSMN1; SMN2LTB4RPPARD | |
| SCHEMBL7974327 | 0.78 | PPARA (0.42) | PPARAPPARGSMN1; SMN2LTB4RPPARD | |
| SCHEMBL7974197 | 0.76 | MRGPRX4 (0.51) | PPARAPPARGSMN1; SMN2LTB4RPTGDR2 | |
| SCHEMBL7976453 | 0.76 | SMN1; SMN2 (0.42) | PPARAPPARGSMN1; SMN2LTB4RPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6248766-B1 | CARDIOVASCULAR DISORDERS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2001-06-19 | — | — | US | disclosed |