Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | CA5A | P35218 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | MMP1 | P03956 | 2/20 | 0.38 |
| ▸ | MMP13 | P45452 | 2/20 | 0.38 |
| ▸ | MMP2 | P08253 | 1/20 | 0.38 |
| ▸ | MMP9 | P14780 | 1/20 | 0.38 |
| ▸ | MMP8 | P22894 | 1/20 | 0.38 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.37 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.37 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.37 |
| ▸ | FAAH | O00519 | 1/20 | 0.37 |
| ▸ | ELANE | P08246 | 1/20 | 0.37 |
| ▸ | PRTN3 | P24158 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17221973 | 0.77 | GAA (0.45) | TSHRSMN1; SMN2CA1CA2CA5A | |
| SCHEMBL563505 | 0.76 | HSD11B1 (0.47) | TSHRSMN1; SMN2HSD11B1HSD17B10KMT2A | |
| SCHEMBL6549890 | 0.73 | CA2 (0.52) | TSHRSMN1; SMN2CA1CA2CA5A | |
| SCHEMBL1457443 | 0.72 | CA1 (0.54) | TSHRSMN1; SMN2CA1CA2CA5A | |
| SCHEMBL7757515 | 0.71 | CA1 (0.46) | TSHRSMN1; SMN2CA1CA2CA5A | |
| SCHEMBL7962765 | 0.71 | ALDH1A1 (0.37) | CA1CA2CA9HSD11B1KMT2A | |
| SCHEMBL3241398 | 0.69 | PRSS1 (0.50) | TSHRSMN1; SMN2CA1CA2CA5A | |
| SCHEMBL7271933 | 0.68 | CA1 (0.42) | TSHRSMN1; SMN2CA1CA2CA5A | |
| SCHEMBL7594223 | 0.67 | PRSS1 (0.52) | TSHRSMN1; SMN2CA1CA2CA5A | |
| SCHEMBL563289 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6262181-B1 | AS COMPONENT OF PHOTORESISTS | ARCH SPECIALTY CHEMICALS, INC. | 2001-07-17 | — | — | US | disclosed |