Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | HSD11B1 | P28845 | 3/20 | 0.35 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.35 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.35 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.34 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.34 |
| ▸ | ABCC9 | O60706 | 1/20 | 0.34 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.34 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.34 |
| ▸ | KCNJ8 | Q15842 | 1/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL563505 | 0.81 | HSD11B1 (0.47) | ALDH1A1HTTHSD11B1POLBKMT2A | |
| SCHEMBL4541609 | 0.76 | RAPGEF4 (0.42) | ALDH1A1HTTHSD11B1SLC1A3SLC1A2 | |
| SCHEMBL384657 | 0.76 | ALDH1A1 (0.44) | ALDH1A1HTTPOLBCYP2C9CYP2C19 | |
| SCHEMBL6932217 | 0.76 | CES2 (0.42) | ALDH1A1HTTHSD11B1POLBMEN1 | |
| SCHEMBL25431421 | 0.75 | RAPGEF4 (0.38) | ALDH1A1ALOX12HTTHSD11B1SLC1A3 | |
| SCHEMBL1743909 | 0.75 | EPHX2 (0.43) | ALDH1A1ALOX12HTTPOLBMEN1 | |
| SCHEMBL6932210 | 0.73 | PARP1 (0.38) | ALDH1A1ALOX12POLBCYP2C19 | |
| SCHEMBL4926645 | 0.72 | RAPGEF4 (0.40) | ALDH1A1HTTHSD11B1SLC1A3SLC1A2 | |
| SCHEMBL7694414 | 0.72 | NPC1 (0.31) | CA9 | |
| SCHEMBL15437896 | 0.72 | SLC1A3 (0.44) | ALDH1A1ALOX12HTTHSD11B1SLC1A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6262181-B1 | AS COMPONENT OF PHOTORESISTS | ARCH SPECIALTY CHEMICALS, INC. | 2001-07-17 | — | — | US | disclosed |