Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.32 |
| ▸ | ACACB | O00763 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7974357 | 0.74 | — | — | |
| SCHEMBL31536590 | 0.72 | GPR119 (0.41) | RECQLGPR119ACACBNPC1RAB9A | |
| SCHEMBL31536544 | 0.72 | GPR119 (0.41) | RECQLGPR119ACACBNPC1RAB9A | |
| SCHEMBL7788983 | 0.71 | ENPP2 (0.36) | RECQLGPR119 | |
| SCHEMBL7974207 | 0.68 | RXRA (0.41) | — | |
| SCHEMBL25797707 | 0.66 | GPR119 (0.42) | GPR119MAPK1 | |
| SCHEMBL25777220 | 0.66 | GPR119 (0.42) | GPR119MAPK1 | |
| SCHEMBL25797633 | 0.66 | GPR119 (0.42) | GPR119MAPK1 | |
| SCHEMBL25777215 | 0.66 | GPR119 (0.42) | GPR119MAPK1 | |
| SCHEMBL25912217 | 0.66 | GPR119 (0.42) | GPR119MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001081317-A1 | CHIRAL IMIDAZOYL INTERMEDIATES FOR THE SYNTHESIS OF 2-(4-IMIDAZOYL)-CYCLOPROPYL DERIVATIVES | GLIATECH, INC. (US) | 2001-11-01 | — | — | WO | disclosed |