Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 3/20 | 0.41 |
| ▸ | RXRB | P28702 | 3/20 | 0.41 |
| ▸ | RXRG | P48443 | 3/20 | 0.41 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.41 |
| ▸ | RARA | P10276 | 1/20 | 0.39 |
| ▸ | RARB | P10826 | 1/20 | 0.39 |
| ▸ | RARG | P13631 | 1/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 9/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.31 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.31 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.31 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.31 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7962818 | 0.82 | EPHX2 (0.38) | EPHX2 | |
| SCHEMBL6136581 | 0.81 | — | — | |
| SCHEMBL6137027 | 0.76 | — | — | |
| SCHEMBL6136723 | 0.76 | — | — | |
| SCHEMBL1828996 | 0.70 | KDM4E (0.39) | ALDH1A1 | |
| SCHEMBL6821893 | 0.68 | ALDH1A1 (0.37) | HDAC4ALDH1A1 | |
| SCHEMBL7962808 | 0.68 | RECQL (0.34) | — | |
| SCHEMBL20558894 | 0.68 | RXRA (0.47) | RXRARXRBRXRGNR4A2RARA | |
| SCHEMBL20558896 | 0.68 | RXRA (0.47) | RXRARXRBRXRGNR4A2RARA | |
| SCHEMBL7842985 | 0.67 | AKR1B1 (0.36) | NR4A2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001081317-A1 | CHIRAL IMIDAZOYL INTERMEDIATES FOR THE SYNTHESIS OF 2-(4-IMIDAZOYL)-CYCLOPROPYL DERIVATIVES | GLIATECH, INC. (US) | 2001-11-01 | — | — | WO | disclosed |