⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7967936 | 0.86 | ROCK2 (0.42) | — | |
| SCHEMBL26351225 | 0.82 | LMNA (0.42) | — | |
| SCHEMBL28588484 | 0.82 | LMNA (0.45) | — | |
| SCHEMBL7002340 | 0.80 | — | — | |
| SCHEMBL7964003 | 0.79 | — | — | |
| SCHEMBL7002778 | 0.79 | — | — | |
| SCHEMBL7002279 | 0.76 | ROCK2 (0.38) | — | |
| SCHEMBL21499423 | 0.75 | — | — | |
| SCHEMBL10623770 | 0.75 | EPHX1 (0.45) | — | |
| SCHEMBL23026449 | 0.73 | EPHX1 (0.48) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11530298-B2 | Poly(phosphoesters) for delivery of nucleic acids | TRANSLATE BIO, INC. (US) | 2022-12-20 | — | — | US | disclosed |
| EP-3638716-B1 | POLY(PHOSPHOESTERS) FOR DELIVERY OF NUCLEIC ACIDS | TRANSLATE BIO INC (US) | 2022-01-05 | — | — | EP | disclosed |
| US-20200277446-A1 | POLY(PHOSPHOESTERS) FOR DELIVERY OF NUCLEIC ACIDS | TRANSLATE BIO, INC. | 2020-09-03 | — | — | US | disclosed |
| EP-3638716-A1 | POLY(PHOSPHOESTERS) FOR DELIVERY OF NUCLEIC ACIDS | Translate Bio, Inc. (US) | 2020-04-22 | — | — | EP | disclosed |
| EP-3252066-B1 | HCV POLYMERASE INHIBITORS | MEDIVIR AB (SE) | 2019-05-22 | — | — | EP | disclosed |
| US-20190085010-A1 | HCV POLYMERASE INHIBITORS | MEDIVIR AB (SE) | 2019-03-21 | — | — | US | disclosed |
| WO-2018231709-A1 | POLY(PHOSPHOESTERS) FOR DELIVERY OF NUCLEIC ACIDS | TRANSLATE BIO, INC. (US) | 2018-12-20 | — | — | WO | disclosed |
| US-10106571-B2 | HCV polymerase inhibitors | MEDIVIR AB (SE) | 2018-10-23 | — | — | US | disclosed |
| US-20180105549-A1 | HCV POLYMERASE INHIBITORS | MEDIVIR AB (SE) | 2018-04-19 | — | — | US | disclosed |
| EP-3252066-A1 | HCV POLYMERASE INHIBITORS | MEDIVIR AB (SE) | 2017-12-06 | — | — | EP | disclosed |
| US-20150175648-A1 | HCV POLYMERASE INHIBITORS | MEDIVIR AB (SE) | 2015-06-25 | — | — | US | disclosed |
| WO-2015056213-A1 | HCV POLYMERASE INHIBITORS | MEDIVIR AB (SE) | 2015-04-23 | — | — | WO | disclosed |
| WO-2015034420-A1 | HCV POLYMERASE INHIBITORS | MEDIVIR AB (SE) | 2015-03-12 | — | — | WO | disclosed |
| US-6204222-B1 | SUITABLE AS HERBICIDES AND FOR DESICCATION/DEFOLIATION OF PLANTS | BASF AKTIENGESELLSCHAFT (DE) | 2001-03-20 | — | — | US | disclosed |
| EP-0637298-B1 | SUBSTITUTED CYCLOHEXENE-1,2-BICARBOXYLIC ACID DERIVATIVES AND RAW MATERIALS FOR PRODUCING THEM | BASF AG (DE) | 1999-03-31 | — | — | EP | disclosed |
| US-5817603-A | HERBICIDES | BASF AKTIENGESELLSCHAFT (DE) | 1998-10-06 | — | — | US | disclosed |
| US-5602074-A | HERBICIDES; PLANT DESICCATION, DEFOLIATION | BASF AKTIENGESELLSCHAFT (DE) | 1997-02-11 | — | — | US | disclosed |
| EP-0641321-A1 | SUBSTITUTED ISOINDOLONES | BASF Aktiengesellschaft (DE) | 1995-03-08 | — | — | EP | disclosed |
| WO-1993024456-A1 | SUBSTITUTED ISOINDOLONES | BASF AKTIENGESELLSCHAFT (DE) | 1993-12-09 | — | — | WO | disclosed |
| WO-1993022280-A1 | SUBSTITUTED CYCLOHEXENE-1,2-BICARBOXYLIC ACID DERIVATIVES AND RAW MATERIALS FOR PRODUCING THEM | BASF AKTIENGESELLSCHAFT (DE) | 1993-11-11 | — | — | WO | disclosed |