SCHEMBL7002279

SCHEMBL7002279

CCCCSC(C)CCO

nearest known ligand 0.38

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ROCK2 O75116 1/20 0.38
EPHX1 P07099 1/20 0.38
ALDH1A1 P00352 3/20 0.38
SMN1; SMN2 Q16637 1/20 0.36
OPRM1 P35372 1/20 0.36
LMNA P02545 3/20 0.35
TSHR P16473 2/20 0.35
HSD17B10 Q99714 1/20 0.35
MEN1 O00255 1/20 0.35
KMT2A Q03164 1/20 0.35
TP53 P04637 1/20 0.33
FDPS P14324 4/20 0.32
NOS3 P29474 1/20 0.32
NOS1 P29475 1/20 0.32
NOS2 P35228 1/20 0.32
MAOA P21397 1/20 0.31
MAOB P27338 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11080948 0.91 EPHX1 (0.48) ROCK2EPHX1ALDH1A1SMN1; SMN2OPRM1
SCHEMBL31167317 0.86 ROCK2 (0.41) ROCK2
SCHEMBL7002340 0.86
Phosphoric Acid SCHEMBL11091217 0.83 FDPS (0.47) EPHX1FDPS
SCHEMBL7967936 0.82 ROCK2 (0.42) ROCK2EPHX1ALDH1A1SMN1; SMN2OPRM1
SCHEMBL7001679 0.81
SCHEMBL26351225 0.78 LMNA (0.42) ROCK2EPHX1ALDH1A1SMN1; SMN2LMNA
SCHEMBL28588484 0.78 LMNA (0.45) ROCK2EPHX1ALDH1A1SMN1; SMN2OPRM1
SCHEMBL24276627 0.77 ALDH1A1 (0.38) EPHX1ALDH1A1SMN1; SMN2OPRM1LMNA
SCHEMBL7002277 0.77 EPHX1 (0.38) EPHX1SMN1; SMN2OPRM1TSHRFDPS

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6525000-B1 N-aminoureas are reacted with formaldehyde to give methyleneimino ureas, cyclizing these to give tetrahydro-4H-1,3,4-oxa(or thia)diazines, and cyclizing the fused triazoles using phosgene; herbicides BASF AKTIENGESELLSCHAFT (DE) 2003-02-25 US disclosed
EP-1095045-B1 METHOD FOR PRODUCING ANELLATED TRIAZOLES AND NEW ANELLATED TRIAZOLES AND THEIR USE BASF AG (DE) 2003-01-15 EP disclosed
EP-0835248-B1 1-AMINO-3-BENZYLURACILS BASF AG (DE) 2001-02-21 EP disclosed
EP-0971904-A1 NOVEL 1-AMINO-3 BENZYL URACILS BASF AKTIENGESELLSCHAFT (DE) 2000-01-19 EP disclosed
WO-1998042682-A1 NOVEL 1-AMINO-3 BENZYL URACILS BASF AKTIENGESELLSCHAFT (DE) 1998-10-01 WO disclosed
EP-0835248-A1 1-AMINO-3-BENZYLURACILS BASF AKTIENGESELLSCHAFT (DE) 1998-04-15 EP disclosed
WO-1997001543-A1 1-AMINO-3-BENZYLURACILS BASF AKTIENGESELLSCHAFT (DE) 1997-01-16 WO disclosed