SCHEMBL7967936

SCHEMBL7967936

CCCCC(C)SCCO

nearest known ligand 0.42

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
ROCK2 O75116 1/20 0.42
ALDH1A1 P00352 3/20 0.38
FDPS P14324 2/20 0.37
SMN1; SMN2 Q16637 2/20 0.36
LMNA P02545 3/20 0.35
TSHR P16473 3/20 0.35
HSD17B10 Q99714 1/20 0.35
MEN1 O00255 1/20 0.35
KMT2A Q03164 1/20 0.35
EPHX1 P07099 1/20 0.34
DNM1 Q05193 1/20 0.32
CA2 P00918 1/20 0.31
MAPK1 P28482 1/20 0.31
OPRM1 P35372 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28588484 0.91 LMNA (0.45) ROCK2ALDH1A1FDPSSMN1; SMN2LMNA
SCHEMBL7963172 0.86
SCHEMBL7002279 0.82 ROCK2 (0.38) ROCK2ALDH1A1FDPSSMN1; SMN2LMNA
SCHEMBL7963567 0.81
SCHEMBL28101271 0.79 EPHX1 (0.48) FDPSSMN1; SMN2LMNATSHRHSD17B10
SCHEMBL27738542 0.79 EPHX1 (0.48) FDPSSMN1; SMN2LMNATSHRHSD17B10
SCHEMBL11080948 0.78 EPHX1 (0.48) ROCK2ALDH1A1FDPSSMN1; SMN2LMNA
SCHEMBL7967933 0.77 FDPS (0.37) FDPSSMN1; SMN2TSHREPHX1DNM1
SCHEMBL1880267 0.77 TSHR (0.32) FDPSSMN1; SMN2TSHREPHX1DNM1
SCHEMBL27802102 0.77 ALDH1A1 (0.38) ALDH1A1FDPSSMN1; SMN2TSHRMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6204222-B1 SUITABLE AS HERBICIDES AND FOR DESICCATION/DEFOLIATION OF PLANTS BASF AKTIENGESELLSCHAFT (DE) 2001-03-20 US disclosed
EP-0637298-B1 SUBSTITUTED CYCLOHEXENE-1,2-BICARBOXYLIC ACID DERIVATIVES AND RAW MATERIALS FOR PRODUCING THEM BASF AG (DE) 1999-03-31 EP disclosed
US-5817603-A HERBICIDES BASF AKTIENGESELLSCHAFT (DE) 1998-10-06 US disclosed
US-5602074-A HERBICIDES; PLANT DESICCATION, DEFOLIATION BASF AKTIENGESELLSCHAFT (DE) 1997-02-11 US disclosed
EP-0641321-A1 SUBSTITUTED ISOINDOLONES BASF Aktiengesellschaft (DE) 1995-03-08 EP disclosed
EP-0637298-A1 SUBSTITUTED CYCLOHEXENE-1,2-BICARBOXYLIC ACID DERIVATIVES AND RAW MATERIALS FOR PRODUCING THEM BASF Aktiengesellschaft (DE) 1995-02-08 EP disclosed
WO-1993024456-A1 SUBSTITUTED ISOINDOLONES BASF AKTIENGESELLSCHAFT (DE) 1993-12-09 WO disclosed
WO-1993022280-A1 SUBSTITUTED CYCLOHEXENE-1,2-BICARBOXYLIC ACID DERIVATIVES AND RAW MATERIALS FOR PRODUCING THEM BASF AKTIENGESELLSCHAFT (DE) 1993-11-11 WO disclosed