Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 3/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | TPMT | P51580 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1328328 | 0.83 | MEN1 (0.49) | MEN1KMT2ANPC1RAB9APOLB | |
| SCHEMBL3060301 | 0.83 | MEN1 (0.49) | MEN1KMT2ANPC1RAB9APOLB | |
| SCHEMBL4004768 | 0.83 | MEN1 (0.49) | MEN1KMT2ANPC1RAB9APOLB | |
| SCHEMBL7963288 | 0.81 | MEN1 (0.48) | MEN1KMT2ANPC1RAB9APOLB | |
| SCHEMBL6361656 | 0.73 | KMT2A (0.50) | MEN1KMT2ANPC1RAB9APOLB | |
| SCHEMBL9371465 | 0.68 | ADRA2A (0.54) | MEN1KMT2ARAB9AHTR1AKDM4E | |
| SCHEMBL13990270 | 0.67 | — | — | |
| SCHEMBL1864860 | 0.67 | NPC1 (0.50) | MEN1KMT2ANPC1RAB9APOLB | |
| SCHEMBL12431900 | 0.67 | PTGS2 (0.38) | MEN1KMT2ANPC1RAB9APOLB | |
| SCHEMBL17400910 | 0.66 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001007409-A1 | CARBAZOLE DERIVATIVES AND THEIR USE AS NEUROPEPTIDE Y5 RECEPTOR LIGANDS | ASTRAZENECA UK LIMITED (GB) | 2001-02-01 | — | — | WO | disclosed |