Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7976883 | 0.89 | KDM4E (0.52) | GAASMN1; SMN2KEAP1KDM4ELMNA | |
| SCHEMBL6477465 | 0.78 | HRH3 (0.49) | SMN1; SMN2LMNAMAPK1ALDH1A1 | |
| SCHEMBL1358701 | 0.77 | KDM4E (0.61) | GAASMN1; SMN2KEAP1KDM4ELMNA | |
| Hydrochloric Acid SCHEMBL11543248 | 0.76 | GLA (0.60) | GAASMN1; SMN2KEAP1KDM4ELMNA | |
| SCHEMBL8616993 | 0.76 | KDM4E (0.59) | GAASMN1; SMN2KEAP1KDM4ELMNA | |
| SCHEMBL5980656 | 0.75 | SMN1; SMN2 (0.54) | GAASMN1; SMN2KEAP1KDM4ELMNA | |
| Sulfuric Acid SCHEMBL11724660 | 0.75 | BLM (0.47) | GAASMN1; SMN2KEAP1KDM4ELMNA | |
| SCHEMBL5910714 | 0.74 | KEAP1 (0.58) | GAASMN1; SMN2KEAP1KDM4ELMNA | |
| SCHEMBL5843494 | 0.74 | KDM4E (0.57) | GAASMN1; SMN2KEAP1KDM4ELMNA | |
| SCHEMBL1726737 | 0.74 | KDM4E (0.57) | GAASMN1; SMN2KEAP1KDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8288380-B2 | Thiophenediamine derivative having urea structure | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 2012-10-16 | — | — | US | disclosed |
| WO-2001007409-A1 | CARBAZOLE DERIVATIVES AND THEIR USE AS NEUROPEPTIDE Y5 RECEPTOR LIGANDS | ASTRAZENECA UK LIMITED (GB) | 2001-02-01 | — | — | WO | disclosed |