Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 4/20 | 0.54 |
| ▸ | DRD2 | P14416 | 11/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.46 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7963515 | 0.83 | CCR1 (0.58) | CCR1DRD2KDM4EKMT2AADRA1A | |
| SCHEMBL7957165 | 0.82 | DRD2 (0.66) | CCR1DRD2ADRA1A | |
| SCHEMBL7960236 | 0.81 | DRD2 (0.63) | CCR1DRD2ADRA1A | |
| SCHEMBL7960076 | 0.81 | DRD2 (0.70) | DRD2KMT2AADRA1A | |
| SCHEMBL7949623 | 0.81 | DRD2 (0.63) | CCR1DRD2KMT2AADRA1A | |
| SCHEMBL7957459 | 0.81 | MEN1 (0.58) | CCR1DRD2KMT2AADRA1A | |
| SCHEMBL7963905 | 0.80 | DRD2 (0.59) | DRD2KMT2AADRA1A | |
| SCHEMBL7949044 | 0.80 | DRD2 (0.59) | DRD2KMT2AADRA1A | |
| SCHEMBL7959857 | 0.80 | DRD2 (0.46) | CCR1DRD2KDM4EKMT2A | |
| SCHEMBL8568581 | 0.78 | OPRM1 (0.63) | CCR1DRD2OPRL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6187774-B1 | N-PIPERAZINYLALKYLINDAZOLE DERIVATIVES; PSYCHOLOGICAL DISORDERS, SCHIZOPHRENIA; SIDE EFFECT REDUCTION | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 2001-02-13 | — | — | US | disclosed |
| EP-0885883-A1 | FUSED HETEROCYCLIC COMPOUNDS AND PHARMACEUTICAL APPLICATIONS THEREOF | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1998-12-23 | — | — | EP | disclosed |