Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 15/20 | 0.63 |
| ▸ | OPRK1 | P41145 | 9/20 | 0.62 |
| ▸ | DRD2 | P14416 | 9/20 | 0.62 |
| ▸ | HTR1A | P08908 | 8/20 | 0.62 |
| ▸ | DRD4 | P21917 | 8/20 | 0.62 |
| ▸ | HTR2A | P28223 | 8/20 | 0.62 |
| ▸ | HTR2C | P28335 | 8/20 | 0.62 |
| ▸ | HTR7 | P34969 | 8/20 | 0.62 |
| ▸ | HTR1D | P28221 | 7/20 | 0.62 |
| ▸ | DRD3 | P35462 | 7/20 | 0.62 |
| ▸ | HTR2B | P41595 | 7/20 | 0.62 |
| ▸ | OPRD1 | P41143 | 7/20 | 0.62 |
| ▸ | HRH2 | P25021 | 6/20 | 0.62 |
| ▸ | DRD1 | P21728 | 6/20 | 0.62 |
| ▸ | DRD5 | P21918 | 6/20 | 0.62 |
| ▸ | SLC6A2 | P23975 | 6/20 | 0.62 |
| ▸ | SLC6A4 | P31645 | 6/20 | 0.62 |
| ▸ | HTR6 | P50406 | 6/20 | 0.62 |
| ▸ | SLC6A3 | Q01959 | 6/20 | 0.62 |
| ▸ | HRH1 | P35367 | 5/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7963905 | 0.86 | DRD2 (0.59) | OPRM1DRD2HTR1ADRD4HTR2A | |
| SCHEMBL14282239 | 0.86 | OPRM1 (0.76) | OPRM1OPRK1DRD2HTR1ADRD4 | |
| SCHEMBL8568579 | 0.84 | OPRM1 (0.58) | OPRM1OPRK1DRD2HTR1ADRD4 | |
| SCHEMBL7949044 | 0.84 | DRD2 (0.59) | OPRM1DRD2HTR1ADRD4HTR2A | |
| Seperidol SCHEMBL124937 | 0.82 | DRD2 (0.80) | OPRM1OPRK1DRD2HTR1ADRD4 | |
| SCHEMBL7959913 | 0.82 | DRD2 (0.52) | OPRM1DRD2OPRL1CCR1 | |
| SCHEMBL7960076 | 0.81 | DRD2 (0.70) | OPRM1DRD2HTR1ADRD4HTR2A | |
| Seperidol SCHEMBL124936 | 0.81 | DRD2 (0.78) | OPRM1OPRK1DRD2HTR1ADRD4 | |
| SCHEMBL11609688 | 0.80 | DRD2 (0.61) | OPRM1OPRK1DRD2HTR1ADRD4 | |
| SCHEMBL11850236 | 0.80 | DRD2 (0.61) | OPRM1OPRK1DRD2HTR1ADRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0885883-A1 | FUSED HETEROCYCLIC COMPOUNDS AND PHARMACEUTICAL APPLICATIONS THEREOF | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1998-12-23 | — | — | EP | disclosed |