Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | DRD4 | P21917 | 2/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 6/20 | 0.42 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | RAD52 | P43351 | 1/20 | 0.40 |
| ▸ | SCN1A | P35498 | 1/20 | 0.40 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.40 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7963764 | 0.84 | MEN1 (0.35) | HTR1AMEN1KMT2AHTT | |
| SCHEMBL7963099 | 0.76 | KMT2A (0.49) | KDM4EL3MBTL1HTR1AMEN1KMT2A | |
| SCHEMBL7965451 | 0.73 | SMN1; SMN2 (0.55) | KDM4EPOLBMAPK1L3MBTL1HTR1A | |
| SCHEMBL7962997 | 0.72 | CYP2D6 (0.50) | KDM4EL3MBTL1HTR1AKMT2ACYP2D6 | |
| Malonic Acid SCHEMBL7953260 | 0.71 | MAPT (0.44) | POLBHTR1AABCB1MAPTLMNA | |
| Acrylic Acid SCHEMBL7963757 | 0.71 | ALDH1A1 (0.38) | POLBMAPK1MEN1KMT2AMAPT | |
| SCHEMBL7967094 | 0.70 | HTR7 (0.54) | KDM4EPOLBMAPK1HTR1AMAPT | |
| SCHEMBL7953344 | 0.68 | KDM4E (0.53) | KDM4EPOLBMAPK1L3MBTL1DRD4 | |
| SCHEMBL4578208 | 0.68 | KDM4E (0.85) | KDM4EPOLBMAPK1L3MBTL1DRD4 | |
| SCHEMBL7966082 | 0.68 | KDM4E (0.48) | KDM4EHTR1AMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6242450-B1 | SUBSTITUTED PIPERIDINES | ELI LILLY AND COMPANY | 2001-06-05 | — | — | US | disclosed |
| EP-0976746-A1 | 5-HT1F antagonists | ELI LILLY AND COMPANY (US) | 2000-02-02 | — | — | EP | disclosed |