Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | CCR5 | P51681 | 2/20 | 0.34 |
| ▸ | HTR1A | P08908 | 3/20 | 0.33 |
| ▸ | SLC6A1 | P30531 | 1/20 | 0.33 |
| ▸ | SLC6A12 | P48065 | 1/20 | 0.33 |
| ▸ | SLC6A11 | P48066 | 1/20 | 0.33 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.33 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.32 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.32 |
| ▸ | DRD3 | P35462 | 1/20 | 0.32 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.32 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7963760 | 0.84 | KDM4E (0.45) | MEN1KMT2AHTR1AHTT | |
| SCHEMBL7953266 | 0.79 | CCR5 (0.34) | CCR5HTR1AITGA4ITGB7HTR2A | |
| SCHEMBL7963100 | 0.76 | SLC6A1 (0.34) | MEN1KMT2ACCR5HTR1ASLC6A1 | |
| SCHEMBL8139378 | 0.76 | SLC6A1 (0.34) | MEN1KMT2ACCR5HTR1ASLC6A1 | |
| SCHEMBL7965454 | 0.75 | OPRL1 (0.36) | MEN1KMT2AHTR1ASLC6A1SLC6A12 | |
| SCHEMBL7965779 | 0.74 | ITGA4 (0.33) | CCR5HTR1AITGA4ITGB7ADRA1A | |
| SCHEMBL7962999 | 0.72 | OPRL1 (0.40) | HTR1A | |
| SCHEMBL7967096 | 0.72 | TUBB4A (0.38) | SLC6A1SLC6A12SLC6A11ADRA1AADRA1B | |
| Acrylic Acid SCHEMBL7963757 | 0.69 | ALDH1A1 (0.38) | MEN1KMT2AITGA4ITGB7HTT | |
| SCHEMBL7966082 | 0.68 | KDM4E (0.48) | MEN1KMT2AHTR1AHTR2ASIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6242450-B1 | SUBSTITUTED PIPERIDINES | ELI LILLY AND COMPANY | 2001-06-05 | — | — | US | disclosed |
| EP-0976746-A1 | 5-HT1F antagonists | ELI LILLY AND COMPANY (US) | 2000-02-02 | — | — | EP | disclosed |