Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1D | P28221 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 7/20 | 0.36 |
| ▸ | HTR7 | P34969 | 6/20 | 0.36 |
| ▸ | HTR1A | P08908 | 6/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.36 |
| ▸ | HTR6 | P50406 | 5/20 | 0.36 |
| ▸ | PPARG | P37231 | 2/20 | 0.36 |
| ▸ | PPARA | Q07869 | 2/20 | 0.36 |
| ▸ | FPR3 | P25089 | 1/20 | 0.36 |
| ▸ | FPR2 | P25090 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | DRD4 | P21917 | 1/20 | 0.35 |
| ▸ | PARP1 | P09874 | 1/20 | 0.35 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.34 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7963831 | 0.85 | DRD2 (0.42) | HTR1DALDH1A1SIGMAR1DRD2PPARG | |
| SCHEMBL7949190 | 0.84 | PPARG (0.43) | SIGMAR1DRD2HTR7HTR1ASLC6A4 | |
| SCHEMBL7963865 | 0.80 | SIGMAR1 (0.46) | SIGMAR1DRD2HTR7HTR1APPARG | |
| SCHEMBL7949602 | 0.80 | DRD2 (0.44) | SIGMAR1DRD2HTR7HTR1ASLC6A4 | |
| SCHEMBL7949194 | 0.80 | PPARG (0.45) | SIGMAR1DRD2HTR7HTR1ASLC6A4 | |
| SCHEMBL7959610 | 0.79 | SIGMAR1 (0.48) | SIGMAR1DRD2HTR1APPARGPPARA | |
| SCHEMBL7949420 | 0.79 | HTR6 (0.43) | SIGMAR1DRD2HTR7HTR1ASLC6A4 | |
| SCHEMBL7961484 | 0.78 | SIGMAR1 (0.55) | SIGMAR1DRD2HTR1APPARGPPARA | |
| SCHEMBL7959645 | 0.77 | CCR3 (0.42) | ALDH1A1DRD2HTR7HTR1AHTR6 | |
| SCHEMBL7964085 | 0.76 | SIGMAR1 (0.55) | SIGMAR1DRD2HTR7HTR1AHTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6187774-B1 | N-PIPERAZINYLALKYLINDAZOLE DERIVATIVES; PSYCHOLOGICAL DISORDERS, SCHIZOPHRENIA; SIDE EFFECT REDUCTION | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 2001-02-13 | — | — | US | disclosed |
| EP-0885883-A1 | FUSED HETEROCYCLIC COMPOUNDS AND PHARMACEUTICAL APPLICATIONS THEREOF | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1998-12-23 | — | — | EP | disclosed |