Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 6/20 | 0.49 |
| ▸ | NPC1 | O15118 | 4/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.47 |
| ▸ | MAPT | P10636 | 8/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 4/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.45 |
| ▸ | ELANE | P08246 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 4/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9353714 | 0.77 | PTGS2 (0.65) | PTGS2RAB9ANPC1KMT2AMEN1 | |
| SCHEMBL7964060 | 0.76 | SMN1; SMN2 (0.62) | PTGS2RAB9ANPC1KMT2AMEN1 | |
| SCHEMBL7977647 | 0.76 | PTGS2 (0.50) | PTGS2RAB9ANPC1KMT2AMEN1 | |
| SCHEMBL9357732 | 0.75 | RAB9A (0.63) | RAB9ANPC1KMT2AMEN1ALDH1A1 | |
| SCHEMBL9357780 | 0.72 | NPC1 (0.61) | RAB9ANPC1KMT2AMEN1ALDH1A1 | |
| SCHEMBL141138 | 0.71 | ALDH1A1 (0.70) | RAB9ANPC1KMT2AMEN1ALDH1A1 | |
| SCHEMBL10989220 | 0.71 | CYP1A2 (0.67) | RAB9ANPC1KMT2AMEN1ALDH1A1 | |
| SCHEMBL9353573 | 0.70 | RAB9A (0.71) | RAB9ANPC1KMT2AMEN1ALDH1A1 | |
| SCHEMBL9357828 | 0.70 | MGAM (0.65) | RAB9ANPC1KMT2AMEN1ALDH1A1 | |
| SCHEMBL9353568 | 0.70 | ALDH1A1 (0.65) | RAB9ANPC1KMT2AMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001034573-A1 | COMPOUNDS | ASTRAZENECA AB (SE) | 2001-05-17 | — | — | WO | claimed |
| WO-2001034573-A1 | COMPOUNDS | ASTRAZENECA AB (SE) | 2001-05-17 | — | — | WO | disclosed |