Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 3/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.41 |
| ▸ | DRD4 | P21917 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 3/20 | 0.39 |
| ▸ | HTR1D | P28221 | 3/20 | 0.39 |
| ▸ | HTR1B | P28222 | 3/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | PARP1 | P09874 | 1/20 | 0.38 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.38 |
| ▸ | EGFR | P00533 | 1/20 | 0.37 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.37 |
| ▸ | HRH1 | P35367 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.36 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.36 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7965634 | 0.82 | HTR1A (0.47) | HRH3DRD4HTR1ASLC6A4 | |
| Bromide SCHEMBL7953920 | 0.70 | MAOB (0.43) | HRH3DRD2SLC6A4 | |
| SCHEMBL7876375 | 0.69 | HTR1A (0.51) | HRH3DRD4HTR1ADRD2SLC6A4 | |
| SCHEMBL8820444 | 0.69 | ADRB3 (0.43) | HRH3DRD4HTR1ADRD2ADRB3 | |
| SCHEMBL7966021 | 0.68 | HTR1A (0.47) | HTR1ASLC6A4 | |
| SCHEMBL7966017 | 0.67 | HTR1A (0.46) | HTR1ASLC6A4 | |
| SCHEMBL9456721 | 0.67 | HTR3A (0.56) | DRD2SLC6A4 | |
| Hydrochloric Acid SCHEMBL11071471 | 0.67 | PARP1 (0.46) | CHRNA7HRH3DRD4PARP1PARP2 | |
| SCHEMBL7884092 | 0.66 | HTR1A (0.51) | HRH3HTR1ADRD2SLC6A4 | |
| SCHEMBL8688791 | 0.66 | CHRNA7 (0.84) | CHRNA7HRH3PARP1PARP2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6242450-B1 | SUBSTITUTED PIPERIDINES | ELI LILLY AND COMPANY | 2001-06-05 | — | — | US | disclosed |
| WO-2000006166-A1 | 5-HT1F ANTAGONISTS | ELI LILLY AND COMPANY (US) | 2000-02-10 | — | — | WO | disclosed |
| EP-0976746-A1 | 5-HT1F antagonists | ELI LILLY AND COMPANY (US) | 2000-02-02 | — | — | EP | disclosed |