Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | PPARD | Q03181 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7994085 | 0.86 | MAPK1 (0.46) | LMNAMAPK1TDP1L3MBTL1PPARD | |
| SCHEMBL6587328 | 0.86 | PPARD (0.53) | LMNAL3MBTL1PPARDKMT2ACYP1A2 | |
| SCHEMBL15518189 | 0.81 | ALDH1A1 (0.58) | LMNAMAPK1TDP1L3MBTL1KMT2A | |
| SCHEMBL1706851 | 0.78 | LMNA (0.45) | LMNAMAPK1TDP1L3MBTL1KMT2A | |
| SCHEMBL7997358 | 0.77 | MEN1 (0.46) | L3MBTL1KMT2ACYP1A2MEN1ALDH1A1 | |
| SCHEMBL10506317 | 0.76 | SMN1; SMN2 (0.60) | LMNAL3MBTL1PPARDKMT2ACYP1A2 | |
| SCHEMBL27298156 | 0.76 | LMNA (0.54) | LMNAMAPK1TDP1L3MBTL1KMT2A | |
| SCHEMBL11814669 | 0.76 | PPARD (0.60) | LMNAL3MBTL1PPARDKMT2ACYP1A2 | |
| SCHEMBL7104178 | 0.76 | LMNA (0.50) | LMNAMAPK1L3MBTL1PPARDKMT2A | |
| SCHEMBL10193137 | 0.76 | PPARD (0.59) | LMNAL3MBTL1PPARDKMT2ACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001034573-A1 | COMPOUNDS | ASTRAZENECA AB (SE) | 2001-05-17 | — | — | WO | disclosed |
| WO-2001034578-A1 | COMPOUNDS WITH ANTI-HELICOBACTER PYLORI ACTIVITY | ASTRAZENECA AB (SE) | 2001-05-17 | — | — | WO | disclosed |